# Botulinum Toxin Type A — Prescription Reference

> Clostridial neurotoxin that cleaves SNAP-25 — prescription-only reference entry

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/botulinum-toxin/
- Brand: Peptide Medix EU
- Category: [Aesthetic Biologics](https://peptidemedixeu.com/en/collections/rx-aesthetic-biologics/)
- CAS number: 93384-43-1
- from €161 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 50 U vial | €161 | BOTULINUM-TOXIN-50-U-VIAL |
| 100 U vial | €280 | BOTULINUM-TOXIN-100-U-VIAL |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **CAS number:** 93384-43-1
- **Molecular weight:** ≈150 kDa neurotoxin; commonly supplied as a ~900 kDa complex with non-toxic accessory proteins, or complex-free
- **Form:** Sterile vacuum-dried or lyophilised powder in a single-use glass vial, reconstituted before use
- **Regulatory status:** Prescription-only biologic medicine (Rx); supplied solely against valid prescription or institutional authorisation
- **Active substance:** Botulinum neurotoxin type A (BoNT/A)
- **Source organism:** Clostridium botulinum, anaerobic culture and purification
- **Structure:** Dichain protein — 100 kDa heavy chain and 50 kDa light chain joined by an interchain disulfide bond
- **Molecular target:** SNAP-25, cleaved by the zinc-dependent endopeptidase light chain
- **Pharmacological effect:** Blocks calcium-dependent acetylcholine release at cholinergic nerve terminals
- **Potency units:** Units defined by a manufacturer-specific mouse LD50 assay; not interchangeable between products
- **Reference sizes listed:** 50 U vial; 100 U vial
- **Storage:** Cold chain per approved labelling — unopened vials refrigerated at 2–8 °C (some presentations frozen); reconstituted product refrigerated and used within the labelled window
- **Intended use:** Reference listing only — prescription medicine, administered exclusively by qualified clinicians

## Description

The active ingredient is serotype A botulinum neurotoxin, made by the anaerobic bacterium Clostridium botulinum. Once purified it is a dichain protein of about 150 kDa: a 100 kDa heavy chain that handles binding to neurons and translocation, joined by a disulfide bond to a 50 kDa light chain that functions as a zinc-dependent endopeptidase. Most commercial products present the neurotoxin within a larger complex of non-toxic accessory proteins, though one purified formulation without those proteins is also on the market.

One detail is essential for identification: each manufacturer defines potency Units with its own mouse assay, so Units belong to a specific product and cannot be exchanged between brands. The 50 U and 100 U presentations shown here merely describe vial strength for reference. Listed for reference.

## Frequently asked questions

### Can botulinum toxin be obtained without a prescription?

No. It is a prescription-only biologic that has to be administered by a qualified clinician; in the United States, quantities above set thresholds are also regulated as a select agent. This page is purely a reference listing, and the product is supplied only on a valid prescription or with documented institutional authorisation.

### How does it block muscle contraction?

The heavy chain attaches to SV2 and ganglioside receptors on cholinergic nerve endings, after which the toxin is taken up by endocytosis. As the vesicle acidifies, the light chain moves into the cytosol, where this zinc endopeptidase cuts SNAP-25. With SNAP-25 cleaved, the SNARE complex can no longer fuse vesicles, and acetylcholine release stops.

### Is a Unit the same for every brand?

No. Each manufacturer sets its Units using its own mouse assay, so a Unit of one product does not equal a Unit of another. Authorised product information states plainly that Units cannot be converted or compared across botulinum toxin products — which is why a Unit figure is always quoted with the brand.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/botulinum-toxin/