# Bronchogen

> AEDL (Ala-Glu-Asp-Leu) tetrapeptide for research on bronchial tissue models

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/bronchogen/
- Brand: Peptide Medix EU
- Category: [Khavinson Bioregulators](https://peptidemedixeu.com/en/collections/khavinson-bioregulators/)
- Purity: ≥99% by HPLC; lot-matched COA available
- from €63 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 20 mg | €63 | BRONCHOGEN-20-MG |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **Molecular formula:** C18H30N4O9
- **Molecular weight:** 446.46 g/mol
- **Amino acid sequence:** Ala-Glu-Asp-Leu (AEDL), linear tetrapeptide
- **Peptide class:** Khavinson short-peptide bioregulator (tetrapeptide)
- **Form:** Lyophilized powder in a sealed glass vial
- **Purity:** ≥99% by HPLC; lot-matched COA available
- **Available sizes:** 20 mg
- **Solubility:** Bacteriostatic or sterile water; readily soluble in aqueous buffers
- **Storage (lyophilized):** −20 °C, sealed and protected from light and moisture
- **Storage (reconstituted):** 2–8 °C, protected from light; use within the study window
- **Tissue association:** Bronchial and lung peptide preparations
- **Research areas:** Bronchial epithelial culture, lung tissue models, epithelial differentiation markers, gene expression
- **Sequence relationship:** Shares the Ala-Glu-Asp core with Cortagen (AEDP) and Cardiogen (AEDR)

## Description

Bronchogen is the synthetic tetrapeptide L-alanyl-L-glutamyl-L-aspartyl-L-leucine — Ala-Glu-Asp-Leu, abbreviated AEDL. In the Khavinson series of short-peptide bioregulators it is the sequence linked to bronchial and lung tissue, and it followed the same route as the rest of the family: researchers first examined an organ-derived peptide extract, then pinpointed a short candidate sequence, and finally adopted the defined synthetic tetrapeptide as the research material.

Of the three Ala-Glu-Asp peptides, AEDL is the hydrophobic one. Cortagen finishes with proline and Cardiogen with arginine, whereas Bronchogen finishes with leucine, an uncharged, branched aliphatic residue. On a backbone of only four residues, that one change noticeably shifts solubility, reversed-phase retention and the ratio of polar to nonpolar surface — which is why the three behave differently under the same analytical method although three-quarters of their sequence is identical.

Laboratory studies with AEDL mainly involve bronchial epithelial cell cultures, rodent lung tissue preparations and expression analyses of epithelial differentiation and surfactant-associated markers. We supply Bronchogen in a 20 mg lyophilised vial, made by solid-phase peptide synthesis and HPLC-purified to a ≥99% specification, with a certificate of analysis for each lot. For laboratory research only.

## Frequently asked questions

### What is Bronchogen?

The synthetic tetrapeptide Ala-Glu-Asp-Leu (AEDL), part of the Khavinson short-peptide bioregulator series, where it is associated with bronchial and lung tissue. It is sold as a lyophilised research chemical exclusively for laboratory use.

### How do you verify its quality?

Every lot is tested by HPLC against a ≥99% purity specification, and the matching certificate of analysis can be requested. It shows the batch number, purity result, identity confirmation and a physical description of the material.

### What difference does the leucine make?

Leucine carries a branched, uncharged and hydrophobic side chain, making AEDL the least polar of the three Ala-Glu-Asp peptides. Solubility and reversed-phase retention shift accordingly, so HPLC methods optimised for Cardiogen or Cortagen frequently need to be adapted.

### Why isn't a CAS number given?

This sequence has no widely accepted CAS registry number, so we leave the field empty instead of printing a value we cannot verify. Its identity is defined by sequence, molecular formula and weight, all confirmed on the lot's COA.

### What are the storage conditions?

Store the sealed lyophilised vial at −20 °C, away from light and humidity. After reconstitution, keep the solution at 2–8 °C for the planned study period, or freeze single-use aliquots so it is not frozen and thawed repeatedly.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/bronchogen/