# Cartalax

> Synthetic Ala-Glu-Asp bioregulator tripeptide used in cartilage research

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/cartalax/
- Brand: Peptide Medix EU
- Category: [Khavinson Bioregulators](https://peptidemedixeu.com/en/collections/khavinson-bioregulators/)
- Purity: ≥98% by HPLC; lot-matched COA available
- from €63 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 20 mg | €63 | CARTALAX-20-MG |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **Molecular formula:** C12H19N3O8
- **Molecular weight:** 333.30 g/mol
- **Amino acid sequence:** H-Ala-Glu-Asp-OH
- **Chain length:** 3 amino acids, free N-terminus and C-terminus
- **Peptide class:** Synthetic short-chain bioregulator (Khavinson peptide family)
- **Form:** Lyophilized powder, sealed glass vial
- **Purity:** ≥98% by HPLC; lot-matched COA available
- **Available sizes:** 20 mg
- **Solubility:** Freely soluble in water and bacteriostatic water; solutions are acidic
- **Storage (lyophilized):** −20 °C, sealed and protected from light and moisture
- **Storage (reconstituted):** 2–8 °C, used within the study window
- **Also known as:** AED peptide, Ala-Glu-Asp, cartilage bioregulator peptide
- **Associated tissue:** Cartilage and connective tissue
- **Related sequences:** Vesugen (Lys-Glu-Asp), Chonluten (Glu-Asp-Gly), Epitalon (Ala-Glu-Asp-Gly), Vilon (Lys-Glu)
- **Research areas:** Chondrocyte biology, cartilage matrix expression, peptide–DNA interaction models, cellular senescence

## Description

Cartalax is the synthetic tripeptide Ala-Glu-Asp (AED), one of the short peptides that came out of the Russian bioregulator programme led by Vladimir Khavinson at the St Petersburg Institute of Bioregulation and Gerontology. There it is classed as the bioregulator for cartilage and connective tissue — the synthetic counterpart of Sigumir, a peptide fraction isolated from animal cartilage.

According to the bioregulator hypothesis, very short tissue-linked peptides work on gene expression rather than through conventional receptors: acidic tri- and tetrapeptides are proposed to enter cells, reach the nucleus and bind promoter regions or histone-associated DNA directly, adjusting the transcription of tissue-specific genes. Cartalax is among the sequences most often used to test this in cartilage and chondrocyte models, and its near relatives — Vesugen (Lys-Glu-Asp), Chonluten (Glu-Asp-Gly) and Epitalon (Ala-Glu-Asp-Gly) — make up a family in which swapping a single residue is claimed to change the target tissue.

It is supplied as lyophilised powder in a sealed 20 mg vial, with a certificate of analysis for each lot. To be clear: bioregulator research comes from a fairly small group of laboratories and journals, and independent confirmation is still scarce. This is not a medicine, supplement or consumer product.

## Frequently asked questions

### How does Cartalax differ from Sigumir?

Sigumir is an extract — a peptide fraction from animal cartilage with an undefined composition. Cartalax is one fully synthetic tripeptide, Ala-Glu-Asp, produced by solid-phase synthesis. As the defined synthetic equivalent within the same programme, it is much easier to work with experimentally.

### What is its relationship to Epitalon?

A close one. Epitalon is Ala-Glu-Asp-Gly — Cartalax's three residues plus a C-terminal glycine. In the bioregulator framework, that one additional residue supposedly moves the tissue association from cartilage to the pineal gland, and this claim is itself a frequent topic of comparative studies.

### Which purity documents are included?

The material is supplied at ≥98% by HPLC, and the certificate for your lot can be requested. Very short peptides such as this usually give clean assays; the COA includes identity by mass spectrometry as well as the HPLC purity value.

### How do I reconstitute and store it?

It dissolves easily in bacteriostatic or sterile water — run the diluent down the side of the vial and swirl gently. The resulting solution is acidic, so buffer it or check the pH before adding it to culture medium. Keep the sealed powder at −20 °C and the solution at 2–8 °C, using it within the study period.

### How solid is the evidence for bioregulator peptides?

Thin. Most studies come from a handful of labs, often in regional journals, with small samples and little independent replication. The suggested mechanism — peptides acting directly on DNA — is unusual and remains a hypothesis. Including scrambled-sequence controls is recommended.

### Why is only one vial size available?

20 mg is the standard fill for every Khavinson bioregulator we list, which keeps lot handling and documentation uniform when researchers compare several family members side by side within one study.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/cartalax/