# Epitalon Nasal Spray

> Ready-mixed Ala-Glu-Asp-Gly tetrapeptide solution in a metered spray bottle

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/epitalon-nasal-spray/
- Brand: Peptide Medix EU
- Category: [Nasal Peptide Sprays](https://peptidemedixeu.com/en/collections/nasal-peptide-sprays/)
- CAS number: 307297-39-8
- from €85 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 15 mL | €85 | EPITALON-NASAL-SPRAY-15-ML |
| 30 mL | €140 | EPITALON-NASAL-SPRAY-30-ML |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **CAS number:** 307297-39-8
- **Molecular formula:** C14H22N4O9
- **Molecular weight:** 390.35 g/mol
- **Amino acid sequence:** H-Ala-Glu-Asp-Gly-OH
- **Peptide class:** Synthetic bioregulator tetrapeptide
- **Form:** Pre-mixed aqueous solution in a bottle with metered spray pump
- **Available sizes:** 15 mL, 30 mL
- **Concentration:** Total peptide content and mg per actuation are printed on the bottle label
- **Metered delivery:** Approximately 0.1 mL per actuation from the pump
- **Purity (raw material):** ≥99% by HPLC; lot-matched COA available
- **Active peptide:** Epitalon (epithalon, AEDG peptide)
- **Vehicle:** Aqueous solution with a preservative system suitable for a multi-actuation bottle
- **Research areas:** Telomerase activity, circadian and pineal signalling, cellular senescence, intranasal delivery models
- **Reconstitution:** None required — supplied pre-mixed and ready to dispense
- **Storage:** 2–8 °C, upright, protected from light; do not freeze the filled bottle

## Description

This is epitalon in intranasal form — the synthetic tetrapeptide Ala-Glu-Asp-Gly that Vladimir Khavinson's group designed as a short analogue of the pineal extract epithalamin. The molecule matches our lyophilised vials exactly (CAS 307297-39-8, C14H22N4O9, 390.35 g/mol), but it comes already dissolved in an aqueous vehicle in a bottle with a metered spray pump, so there is nothing to weigh, reconstitute or dissolve.

This format exists because the route of delivery is a research variable in its own right. Comparing intranasal and parenteral administration of small peptides is an established strand of the literature, driven by reports that low-molecular-weight compounds can travel from nose to brain via olfactory and trigeminal pathways. Epitalon's tiny size and excellent water solubility make it a convenient probe for such route comparisons, in addition to the telomerase, circadian and senescence topics it is usually studied for.

The peptide raw material is tested by an independent lab to ≥99% HPLC purity, and the lot's Certificate of Analysis can be viewed before purchase. The finished solution is filled into 15 mL and 30 mL bottles; each label states total peptide content and the amount delivered per spray.

## Frequently asked questions

### What distinguishes this from epitalon vials?

Nothing about the molecule — it is Ala-Glu-Asp-Gly, 390.35 g/mol, in both. What changes is the format: a ready-mixed aqueous solution in a metered spray bottle instead of lyophilised powder needing reconstitution, making it the convenient option for studies of the intranasal route.

### How much epitalon is in a bottle?

Each label shows the lot number, the total peptide content and the dose per spray, and the lot's Certificate of Analysis documents both values. Bottles come in 15 mL and 30 mL sizes.

### How do you verify purity?

The epitalon used to make the solution is tested by an independent lab using reverse-phase HPLC (≥99%), with mass spectrometry confirming the expected 390.35 g/mol. You can view the lot COA on this page before ordering.

### Should the bottle be refrigerated?

Yes. As the peptide is already dissolved, keep the bottle at 2–8 °C, upright and in the dark, and never freeze it — freezing a filled spray bottle can break the pump and cause precipitation when it thaws.

### Why are small peptides of interest for intranasal studies?

Molecules under about 1000 g/mol are the ones most investigated for nose-to-brain transport via olfactory and trigeminal routes. At 390.35 g/mol, epitalon falls comfortably within that range, so it appears in route-comparison studies as well as in its own research field.

---

All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/epitalon-nasal-spray/