# Glutathione Brightening Cream

> 50 g emollient cream containing reduced L-glutathione, for topical research

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/glutathione-cream/
- Brand: Peptide Medix EU
- Category: [Cosmetic Signal Peptides](https://peptidemedixeu.com/en/collections/cosmetic-peptides/)
- from €46 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 50 g | €46 | GLUTATHIONE-CREAM-50-G |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **Peptide class:** Non-ribosomal gamma-linked tripeptide
- **Form:** Opaque emollient cream in a screw-top jar
- **Available sizes:** 50 g
- **Active:** Reduced L-glutathione (GSH), gamma-L-glutamyl-L-cysteinyl-glycine
- **Peptide purity input:** ≥99% by HPLC; lot-matched COA available
- **Active loading:** Stated on the jar label for your lot
- **CAS number (active):** 70-18-8
- **Molecular formula (active):** C10H17N3O6S
- **Molecular weight (active):** 307.32 g/mol
- **Reactive group:** Free cysteinyl thiol (−SH), oxidises to the GSSG disulfide dimer
- **Vehicle:** Oil-in-water emollient cream base, no added fragrance
- **Research areas:** Topical antioxidant delivery, melanogenesis and tyrosinase models, vehicle and occlusion effects, thiol stability in formulation
- **Compatibility note:** Avoid contact with oxidising agents and metal ions such as copper or iron, which accelerate thiol oxidation
- **Storage:** Cool and dark, ideally 2–8 °C; keep the jar tightly closed

## Description

Reduced L-glutathione — gamma-L-glutamyl-L-cysteinyl-glycine, the tripeptide with the unusual gamma link (CAS 70-18-8) — is dispersed here in an emollient cream and packed in a 50 g jar. The glutathione is the same ≥99% HPLC-pure input we use for our lyophilised vials; only the vehicle is different, and in topical research the vehicle is seldom a trivial detail.

Inside cells, glutathione is the principal thiol antioxidant, and nearly every property studied depends on the free sulfhydryl of its cysteine. Pigmentation research reports that it may disrupt melanin formation in several proposed ways: by acting on tyrosinase directly, by trapping reactive intermediates of the melanin pathway, and by tilting production from eumelanin towards pheomelanin. This mix of mechanisms is why both topical and systemic glutathione products keep appearing in the depigmentation literature.

## Frequently asked questions

### Is this the same glutathione as in your vials?

Yes — identical reduced L-glutathione (same CAS number, formula and molecular mass) from ≥99% HPLC-pure raw material. Only the format differs: here it sits in an emollient cream instead of arriving as lyophilised powder for you to dissolve.

### Why test a cream rather than a simple solution?

Often the vehicle is exactly what is being studied. A cream leaves an occlusive film that alters stratum corneum hydration, contact time and the partitioning of a hydrophilic molecule. Studies of permeation, occlusion or vehicle effects need a formulated test article, not a solution in a beaker.

### Does glutathione stay stable in a cream?

Exposed to air, its free thiol oxidises into the GSSG disulfide dimer, and metals like copper and iron speed this up considerably. Cold, dark storage with the lid tight slows the process, yet studies should measure the reduced fraction when the cream is used instead of relying on the labelled content.

### Which documents are provided?

The certificate of analysis for the glutathione lot used — HPLC purity ≥99% and identity confirmation. The jar label states how much active the finished cream contains. Please quote the lot number when you ask for the COA.

### Can it be used together with GHK-Cu products?

Only if the experiment is designed for it. GHK-Cu is a copper complex and glutathione a potent thiol reductant, so their chemistries interact: copper speeds thiol oxidation, and thiols can disrupt copper binding. Unless that interaction is what you are studying, test them separately.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/glutathione-cream/