# Glutathione Nasal Spray

> Ready-mixed reduced L-glutathione solution in a 15 mL or 30 mL metered pump

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/glutathione-nasal-spray/
- Brand: Peptide Medix EU
- Category: [Nasal Peptide Sprays](https://peptidemedixeu.com/en/collections/nasal-peptide-sprays/)
- CAS number: 70-18-8
- from €72 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 15 mL | €72 | GLUTATHIONE-NASAL-SPRAY-15-ML |
| 30 mL | €119 | GLUTATHIONE-NASAL-SPRAY-30-ML |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **CAS number:** 70-18-8
- **Molecular formula:** C10H17N3O6S
- **Molecular weight:** 307.32 g/mol
- **Peptide class:** Non-ribosomal gamma-linked tripeptide
- **Form:** Pre-mixed aqueous solution in a bottle with a metered spray pump
- **Available sizes:** 15 mL, 30 mL
- **Concentration:** Fill strength printed on the bottle label and restated on the lot-matched COA
- **Active compound:** Reduced L-glutathione (GSH)
- **Purity (raw material):** ≥99% by HPLC; lot-matched COA available
- **Structure:** gamma-L-Glutamyl-L-cysteinyl-glycine, reduced form
- **Reactive group:** Free cysteinyl thiol (−SH); oxidises to the GSSG disulfide dimer
- **Research areas:** Redox homeostasis, glutathione peroxidase and S-transferase activity, oxidative stress models, intranasal and mucosal delivery
- **Reconstitution:** None required — supplied pre-mixed and ready to dispense
- **Storage:** 2–8 °C, upright, protected from light; do not freeze the filled bottle
- **Stability note:** Thiol solutions oxidise on standing and faster when warm or alkaline — keep cold and use within the study window

## Description

This product provides reduced L-glutathione (GSH) as a ready-to-use aqueous research solution in 15 mL or 30 mL bottles with a metered pump. Glutathione — gamma-L-glutamyl-L-cysteinyl-glycine, CAS 70-18-8 — is a tripeptide with an atypical gamma link and the most abundant small thiol in mammalian cells. That gamma bond between glutamate and cysteine makes it resistant to standard aminopeptidases, while the free thiol on its cysteine performs its redox chemistry.

Within cells, GSH supplies electrons to glutathione peroxidases, is conjugated to substrates by glutathione S-transferases during phase II detoxification, and keeps protein thiols in their reduced state. When oxidised, two GSH molecules join to form the disulfide GSSG, and the GSH/GSSG ratio is one of the standard measures of redox status. That same reactivity is why formulation matters: thiols oxidise while standing, especially when warm, alkaline or exposed to air and trace metals.

The spray format means labs comparing delivery routes don't have to weigh out and reconstitute powder before every session. It arrives pre-mixed, with its concentration printed on the label and repeated on the lot's Certificate of Analysis. The glutathione raw material is HPLC-tested by an independent lab to ≥99% purity.

## Frequently asked questions

### What is the concentration of the spray?

The strength of your fill appears on the bottle label and is confirmed on the Certificate of Analysis for your batch, so you can check per-spray calculations against a documented figure rather than an assumption. Bottles are available in 15 mL and 30 mL.

### Is the glutathione tested independently?

Yes. An independent lab confirms by HPLC that the reduced L-glutathione input is ≥99% pure and runs identity tests; the COA for your batch is available. Compare the bottle's lot number with the COA before recording results.

### Must it be reconstituted?

No — it comes pre-mixed as an aqueous solution, with no weighing, solvent or filtration required. Removing reconstitution variability from route-comparison experiments is the main reason labs pick the spray.

### How does it differ from the glutathione vial?

Same molecule, different format. The vial contains lyophilised powder (600 mg or 1500 mg) that you reconstitute; the spray is a ready-made solution in a metered pump. Powder remains the more stable form for long storage, for the same reason solutions oxidise.

### Why is storage so critical for glutathione?

The free cysteine thiol is the reactive centre, and it oxidises to the GSSG disulfide when exposed to air, heat, alkaline pH or trace metals. Keeping the bottle cold, dark and upright and using it quickly keeps the reduced share nearer the labelled value.

### Is glutathione really a peptide?

Yes, though an atypical one: a tripeptide in which glutamate and cysteine are linked through a gamma-carboxyl instead of a normal alpha-peptide bond, which is why most aminopeptidases can't cleave it. Formula C10H17N3O6S, mass 307.32 g/mol.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/glutathione-nasal-spray/