# KPV

> Lys-Pro-Val — the C-terminal tripeptide of alpha-MSH, in lyophilised vials

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/kpv/
- Brand: Peptide Medix EU
- Category: [Anti-Inflammatory Peptides](https://peptidemedixeu.com/en/collections/anti-inflammatory-peptides/)
- Purity: ≥99% by HPLC; lot-matched COA available
- CAS number: 67727-97-3
- from €42 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 5 mg | €42 | KPV-5-MG |
| 10 mg | €63 | KPV-10-MG |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **CAS number:** 67727-97-3
- **Molecular formula:** C16H30N4O4
- **Molecular weight:** 342.43 g/mol
- **Amino acid sequence:** Lys-Pro-Val
- **Chain length:** 3 amino acids (tripeptide)
- **Peptide class:** Melanocortin-derived tripeptide; C-terminal fragment of alpha-MSH (11–13)
- **Form:** Lyophilized powder, sealed glass vial with crimped stopper
- **Purity:** ≥99% by HPLC; lot-matched COA available
- **Available sizes:** 5 mg, 10 mg
- **Solubility:** Freely soluble in bacteriostatic or sterile water
- **Storage (lyophilized):** −20 °C, sealed and protected from light and moisture
- **Storage (reconstituted):** 2–8 °C, protected from light, used within the study window
- **Research areas:** Inflammatory signalling, NF-kappa B pathway, intestinal and dermal inflammation models

## Description

KPV is a three-residue peptide — lysine, proline, valine — copying the final three amino acids of alpha-melanocyte-stimulating hormone. It is among the shortest sequences in current inflammation research, and that shortness is precisely what makes it useful: in cell studies the fragment keeps the anti-inflammatory character ascribed to the parent hormone but lacks the melanocortin-receptor activity behind alpha-MSH's effects on pigmentation.

We make it by solid-phase synthesis, purify it by reversed-phase HPLC to ≥99% and fill it as lyophilised powder into sealed glass vials of 5 mg or 10 mg. At only 342 g/mol, each milligram contains many more moles than a longer peptide would, so these vial sizes stretch a long way in plate-based or animal studies.

## Frequently asked questions

### What is KPV?

A synthetic tripeptide of lysine, proline and valine that matches the last three residues of alpha-melanocyte-stimulating hormone. We supply it as a lyophilised research powder; it is chiefly studied in models of inflammatory signalling and intestinal epithelial function.

### How is KPV different from alpha-MSH?

Alpha-MSH is a 13-residue hormone acting on melanocortin receptors, influencing both pigmentation and inflammation. KPV consists of only its last three residues; studies report that it retains the anti-inflammatory character without the receptor-driven pigmentation activity of the whole hormone.

### Do you provide a certificate of analysis?

Yes. Each lot is analysed by reversed-phase HPLC to ≥99% purity, with mass confirmation of the expected 342.43 g/mol, and the certificate bearing your vial's lot number can be requested before or after you order.

### Which size should I buy?

Both go far, because the peptide is so light: at 342 g/mol, one milligram contains many more moles than a milligram of a 30-residue peptide. Take 5 mg for pilots and 10 mg for longer series.

### What solvent is KPV usually dissolved in?

Most labs use bacteriostatic or sterile water, in which the tripeptide dissolves easily to a clear solution; buffers are chosen when an assay needs controlled pH. Solvent choice is part of the study design and is up to the researcher.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/kpv/