# Matrixyl Serum 3000

> Water-based serum pairing palmitoyl tripeptide-1 with palmitoyl tetrapeptide-7 — 30 mL

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/matrixyl-serum/
- Brand: Peptide Medix EU
- Category: [Cosmetic Signal Peptides](https://peptidemedixeu.com/en/collections/cosmetic-peptides/)
- from €55 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 30 mL | €55 | MATRIXYL-SERUM-30-ML |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **Peptide class:** Lipidated matrikines / collagen- and immunoglobulin-derived signal peptides
- **Form:** Clear low-viscosity aqueous serum in a 30 mL bottle
- **Available size:** 30 mL
- **Active peptides:** Palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7
- **INCI names:** Palmitoyl Tripeptide-1; Palmitoyl Tetrapeptide-7
- **Palmitoyl tripeptide-1 sequence:** Palmitoyl-Gly-His-Lys (Pal-GHK)
- **Palmitoyl tripeptide-1 CAS:** 147732-56-7
- **Palmitoyl tetrapeptide-7 sequence:** Palmitoyl-Gly-Gln-Pro-Arg (Pal-GQPR)
- **Palmitoyl tetrapeptide-7 CAS:** 221227-05-0
- **Vehicle:** Aqueous base with humectant and solubiliser; no added fragrance or colourant
- **Peptide purity input:** High-purity HPLC-tested peptides with lot-matched COA
- **Research areas:** Procollagen and glycosaminoglycan synthesis, ECM remodelling, cytokine markers in dermal models, skin permeation
- **Storage:** 2–8 °C preferred, protected from light; keep the closure tight

## Description

This serum is ready to use and water-based, built on the pair of signal peptides known from “3000”-type formulas: palmitoyl tripeptide-1, which is Pal-Gly-His-Lys, and palmitoyl tetrapeptide-7, which is Pal-Gly-Gln-Pro-Arg. Each carries a palmitic acid on its N-terminus; this raises their affinity for fat and helps them move into the lipid-rich barrier of the skin, which unmodified water-loving peptides find hard to cross.

The two derive from unrelated parent sequences and are investigated for different reasons. GHK is the tripeptide discovered in human blood plasma during the 1970s and studied widely in matrix and copper-binding research; GQPR comes from immunoglobulin G and appears in studies of cytokine signalling in skin models. The idea behind the 3000-type complex is to combine a signal linked to matrix repair with a fragment linked to inflammation — which is why comparison studies usually test each peptide on its own as well as together.

It is different from our Matrixyl vial, which contains palmitoyl pentapeptide-4 (Pal-KTTKS) as freeze-dried powder for labs to formulate themselves. The serum saves you that step: a thin, water-based liquid in a 30 mL bottle, made from peptide inputs that were released at high HPLC purity and documented per lot. It is intended for lab and formulation research only and is not an authorised cosmetic or medicinal product.

## Frequently asked questions

### How is this different from the Matrixyl vial?

The vial contains palmitoyl pentapeptide-4 (Pal-KTTKS) as lyophilised powder for you to formulate. The serum is a finished water-based preparation using another pair — palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7 — so both the peptides and the workflow are different.

### Is palmitoyl tripeptide-1 the same as GHK-Cu?

No. Both are built on the Gly-His-Lys sequence, but palmitoyl tripeptide-1 has a fatty-acid tail and no copper attached, whereas GHK-Cu is the plain tripeptide holding a copper(II) ion. That copper is central to what GHK-Cu does chemically, and it is absent from this serum.

### What is the purpose of palmitoylation?

Short, water-loving peptides don't move well into the lipid layers of the stratum corneum. Adding a 16-carbon palmitoyl chain increases lipophilicity and improves that partitioning — a delivery-focused formulation strategy that leaves the signalling sequence itself unchanged.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/matrixyl-serum/
