# MOTS-c Oral Capsules

> MOTS-c in oral research capsules — 5 mg each, 30 per bottle

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/mots-c-oral/
- Brand: Peptide Medix EU
- Category: [Mitochondrial Peptides](https://peptidemedixeu.com/en/collections/mitochondrial-peptides/)
- Purity: ≥99% by HPLC; lot-matched COA available
- CAS number: 1627580-64-6
- from €97 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 5 mg · 30 capsules | €97 | MOTS-C-ORAL-5-MG-30-CAPSULES |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **CAS number:** 1627580-64-6
- **Molecular formula:** C101H152N28O22S2
- **Molecular weight:** 2174.55 g/mol
- **Amino acid sequence:** Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- **Chain length:** 16 amino acids
- **Form:** Oral capsule in a sealed bottle with tamper-evident closure
- **Peptide per capsule:** 5 mg MOTS-c
- **Available size:** 30 capsules (150 mg total peptide per bottle)
- **Peptide purity:** ≥99% by HPLC; lot-matched COA available
- **Active peptide:** MOTS-c, mitochondrial-derived peptide (MDP)
- **Genomic origin:** Short open reading frame within the mitochondrial 12S rRNA gene
- **Research areas:** AMPK signalling, one-carbon and folate metabolism, glucose and lipid handling, oral peptide stability and bioavailability, exercise physiology
- **Storage:** Cool, dry and dark; refrigeration extends shelf stability
- **Preparation required:** None — fixed unit content, no reconstitution step

## Description

MOTS-c is a 16-residue peptide encoded in the mitochondrial 12S rRNA gene instead of nuclear DNA, making it one of a handful of mitochondrial-genome peptides alongside humanin and the SHLPs. Here it is offered as a fixed-dose oral capsule of 5 mg, thirty capsules per sealed bottle, made from peptide of ≥99% HPLC purity with a certificate of analysis for each lot.

The peptide is the same one found in our lyophilised vials: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg, C101H152N28O22S2, roughly 2174.55 g/mol. Studies link it to AMPK activation, the folate–methionine one-carbon cycle, the handling of glucose and lipids, and — under metabolic stress — movement into the nucleus, where it reportedly affects adaptive gene expression.

## Frequently asked questions

### What is the MOTS-c content per capsule?

Each capsule contains 5 mg of MOTS-c, and a sealed bottle holds 30 of them — 150 mg of peptide altogether. As the content is set during manufacture, study designs based on whole capsules need no weighing or reconstitution at all.

### Can MOTS-c be absorbed when taken orally?

Probably very little of it. Peptides this large are usually broken down by stomach acid and gut enzymes and cross the intestinal wall poorly, so assume low absorption into the blood unless your own study proves otherwise. The capsules are meant for research on stability, formulation and effects within the gut — not as a replacement for injecting the peptide.

### Is a certificate of analysis available?

Yes. The certificate for the peptide in your capsule batch reports ≥99% purity by HPLC and confirms identity by mass spectrometry. To request it, give us the lot number shown on the bottle label.

### What does “mitochondrial-derived peptide” mean?

It means the peptide's gene lies in the mitochondria's own DNA — in a short reading frame — rather than in the cell nucleus. MOTS-c is encoded in the 12S rRNA gene; the best-known others of its kind are humanin and the SHLP peptides. Researchers study them as messages sent from mitochondria to the rest of the cell.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/mots-c-oral/