# NAD+ Nasal Spray

> Ready-mixed NAD+ research solution for intranasal work, 15 mL metered pump

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/nad-plus-nasal-spray/
- Brand: Peptide Medix EU
- Category: [Nasal Peptide Sprays](https://peptidemedixeu.com/en/collections/nasal-peptide-sprays/)
- CAS number: 53-84-9
- from €123 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 15 mL · 300 mg | €123 | NAD-PLUS-NASAL-SPRAY-15-ML-300-MG |
| 15 mL · 600 mg | €191 | NAD-PLUS-NASAL-SPRAY-15-ML-600-MG |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **CAS number:** 53-84-9
- **Molecular formula:** C21H27N7O14P2
- **Molecular weight:** 663.43 g/mol
- **Form:** Pre-mixed aqueous solution, 15 mL bottle with metered spray pump
- **Available sizes:** 15 mL (300 mg total), 15 mL (600 mg total)
- **Concentration:** 20 mg/mL (300 mg fill) or 40 mg/mL (600 mg fill)
- **Purity (raw material):** ≥99% by HPLC; lot-matched COA available
- **Active compound:** NAD+ (nicotinamide adenine dinucleotide), free acid
- **Compound class:** Pyridine dinucleotide coenzyme (small molecule, not a peptide)
- **Research areas:** Mitochondrial energy metabolism, sirtuin and PARP biology, NAD+ salvage pathway, intranasal delivery models
- **Reconstitution:** None required — supplied pre-mixed and ready to dispense
- **Storage:** 2–8 °C, upright, protected from light; do not freeze the filled bottle
- **Stability note:** NAD+ in aqueous solution degrades faster at warm or alkaline conditions — keep cold and use within the study window

## Description

This is NAD+ (nicotinamide adenine dinucleotide) dissolved in water and ready for research use, in a 15 mL bottle topped with a metering pump. NAD+ (CAS 53-84-9) is a coenzyme made of two nucleotides joined together; it carries electrons through glycolysis, the Krebs cycle and oxidative phosphorylation, and is also used up by sirtuin deacetylases, PARP DNA-repair enzymes and CD38. Because these enzymes consume it all the time, the amount in a cell keeps shifting, and NAD+ supply has become one of the most intensively studied factors in research on mitochondria and cellular ageing.

With the spray, labs comparing different routes of administration no longer need to weigh, dissolve and sterile-filter powder before every session. It arrives ready-made at a known strength — either 300 mg or 600 mg of NAD+ in the 15 mL bottle, which is 20 or 40 mg per millilitre — well suited to nasal and mucosal-absorption models in which a consistent volume per spray matters more than a series of dilutions.

The nasal route is of interest because its epithelium is thin, well vascularised and close to olfactory and trigeminal pathways that have been investigated as ways around first-pass metabolism in the liver. Whether a particular molecule crosses in useful amounts depends on the compound and is still being researched — and NAD+, a large, very polar, negatively charged dinucleotide, is exactly why route-comparison studies continue.

## Frequently asked questions

### What amount of NAD+ is in a bottle?

Both versions come in the same 15 mL bottle: one contains 300 mg (20 mg/mL), the other 600 mg (40 mg/mL). The strength is printed on the label and stated again on the lot certificate, so you can verify your calculations against a documented value.

### Is the NAD+ independently tested, with a COA I can see?

Yes. An outside laboratory checks the NAD+ used in the spray by HPLC, confirming at least 99% purity and verifying identity; the certificate for your batch is available. Make sure the lot on the bottle matches before you record data.

### Must I reconstitute anything?

No — it arrives as a finished aqueous solution, with no weighing, solvent or filtering needed. Removing reconstitution variability from route-comparison experiments is the main reason labs choose the spray.

### How do I store the bottle?

Refrigerate it at 2–8 °C, standing up and shielded from light, and never freeze it — freezing can crack the glass or ruin the pump. Dissolved NAD+ breaks down faster than the dry powder, so keep it cold and use it up within a short time.

### Should NAD+ be regarded as a peptide?

No. NAD+ is a coenzyme built from two nucleotides — nicotinamide mononucleotide joined to adenosine monophosphate (C21H27N7O14P2). We list it among our research peptides because the same mitochondrial and longevity studies use both, not because they share a structure.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/nad-plus-nasal-spray/