# Pal-AHK (Palmitoyl Tripeptide-3)

> Palmitoylated Ala-His-Lys tripeptide for hair-follicle and formulation studies

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/pal-ahk/
- Brand: Peptide Medix EU
- Category: [Hair Research Peptides](https://peptidemedixeu.com/en/collections/hair-peptides/)
- Purity: ≥99% by HPLC; lot-matched COA available
- from €178 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 200 mg | €178 | PAL-AHK-200-MG |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **Molecular formula:** C31H56N6O5
- **Molecular weight:** 592.80 g/mol
- **Peptide class:** N-terminally lipidated signal tripeptide
- **Form:** Lyophilized amphiphilic peptide powder, sealed glass vial
- **Purity:** ≥99% by HPLC; lot-matched COA available
- **Solubility:** Poorly water-soluble; commonly evaluated with a validated co-solvent or surfactant vehicle
- **Available size:** 200 mg
- **Sequence:** Palmitoyl-Ala-His-Lys-OH (Pal-AHK)
- **Also known as:** Pal-AHK, Palmitoyl AHK, Palmitoyl Tripeptide-3
- **Copper status:** No coordinated copper added; not AHK-Cu
- **Research areas:** Dermal-papilla cell models, follicle biology, extracellular-matrix signaling and topical peptide partitioning
- **Storage:** −20 °C lyophilized, protected from light and moisture

## Description

Pal-AHK — listed in most catalogues as Palmitoyl Tripeptide-3 — is Ala-His-Lys acylated with palmitic acid at its N-terminus. The 16-carbon fatty chain turns a small, water-soluble tripeptide into an amphiphile that moves more easily into lipid phases and onto interfaces. Palmitic acid is a saturated C16 acid attached via a stable amide bond, so the lipid is an integral part of the molecule, not something that detaches.

Its AHK core is a close relative of the copper peptide AHK-Cu. In the unmodified tripeptide, copper is held by the terminal amine together with the histidine imidazole — and acylating that amine takes away one of those anchor points. Pal-AHK carries no bound copper and is investigated mainly as a lipidated signal peptide in dermal papilla, follicle and topical-delivery models. Data specific to Pal-AHK are far sparser than for AHK-Cu or GHK-Cu, so do not borrow mechanisms or results from those compounds without direct controls.

Each 200 mg vial holds lyophilised Pal-Ala-His-Lys (C31H56N6O5, 592.80 g/mol). As an amphiphile rather than a freely water-soluble peptide, how it dissolves matters as much as how much you weigh. HPLC-tested, with a certificate of analysis for each lot, and supplied purely for laboratory formulation and cell-model research — not as a cosmetic, medicine or personal-use product.

## Frequently asked questions

### Are Pal-AHK and AHK-Cu interchangeable?

No. Pal-AHK is Ala-His-Lys carrying an N-terminal palmitoyl chain and no copper; AHK-Cu is the copper(II) complex of the non-lipidated tripeptide. Mass, solubility, colour and coordination chemistry all differ.

### Why is it listed among hair peptides?

Specialist catalogues and the sparse research discussion place it mainly next to AHK-Cu in dermal papilla and follicle-model studies. The category reflects that research setting — it is not a claim that the raw peptide affects hair.

### Is there a standard CAS number for Pal-AHK?

We could not confirm a universally reliable CAS entry for this exact Pal-Ala-His-Lys-OH form, so we deliberately identify it by sequence, formula and molecular weight instead of quoting a doubtful registry number.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/pal-ahk/