# Semax Nasal Spray

> Ready-mixed Semax heptapeptide research solution in a 15 mL metered spray bottle

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/semax-nasal-spray/
- Brand: Peptide Medix EU
- Category: [Nasal Peptide Sprays](https://peptidemedixeu.com/en/collections/nasal-peptide-sprays/)
- CAS number: 80714-61-0
- from €85 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 15 mL · 10 mg | €85 | SEMAX-NASAL-SPRAY-15-ML-10-MG |
| 15 mL · 20 mg | €140 | SEMAX-NASAL-SPRAY-15-ML-20-MG |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **CAS number:** 80714-61-0
- **Molecular formula:** C37H51N9O10S
- **Molecular weight:** 813.93 g/mol
- **Amino acid sequence:** Met-Glu-His-Phe-Pro-Gly-Pro
- **Peptide class:** Synthetic ACTH(4–10) fragment analogue (heptapeptide)
- **Form:** Pre-mixed aqueous solution, 15 mL bottle with metered spray pump
- **Available sizes:** 15 mL (10 mg total), 15 mL (20 mg total)
- **Concentration:** Approximately 0.67 mg/mL (10 mg fill) or 1.33 mg/mL (20 mg fill)
- **Purity (raw material):** ≥99% by HPLC; lot-matched COA available
- **Amino acid count:** 7 residues
- **Research areas:** BDNF and NGF expression, TrkB signalling, attention and memory paradigms, cerebral ischaemia models
- **Reconstitution:** None required — supplied pre-mixed and ready to dispense
- **Storage:** 2–8 °C, upright, protected from light; do not freeze the filled bottle

## Description

Here the synthetic seven-residue peptide Semax comes dissolved in water and ready to use, in a 15 mL bottle with a metering pump. (Identity: Met-Glu-His-Phe-Pro-Gly-Pro, CAS 80714-61-0.) Semax started from the ACTH(4–10) fragment of adrenocorticotropic hormone, to which three residues — Pro-Gly-Pro — were added at the carboxyl end. That single change removes the parent hormone's action on the adrenal glands and also protects the peptide from the exopeptidases that would otherwise remove a short linear chain within minutes.

The 15 mL bottle comes in two fills — 10 mg (about 0.67 mg/mL) or 20 mg (about 1.33 mg/mL). As the solution is pre-formulated, labs comparing intranasal delivery with injected or oral formats can start from a documented concentration without weighing and reconstituting in between, removing a common source of variation between sessions.

## Frequently asked questions

### What quantity of Semax does each bottle hold?

Both come in a 15 mL bottle: 10 mg of Semax gives about 0.67 mg/mL, and 20 mg gives about 1.33 mg/mL. Your bottle's precise concentration appears on its label and again on the lot's Certificate of Analysis.

### Is the Semax independently analysed, with a COA?

Yes. The peptide in the formulation is tested by an independent lab with HPLC to ≥99% purity and identity-confirmed by mass spectrometry; its lot Certificate of Analysis is available. Always compare the bottle's lot number with the COA before recording data.

### What is Semax in chemical terms?

A synthetic seven-residue peptide — Met-Glu-His-Phe-Pro-Gly-Pro, CAS 80714-61-0, C37H51N9O10S, 813.93 g/mol — an ACTH(4–10) analogue lengthened with Pro-Gly-Pro, which slows enzymatic breakdown and has no adrenal-stimulating activity.

### Must the spray be reconstituted?

No. It arrives pre-mixed and ready to use — the key practical difference from the lyophilised Semax vial. Skipping reconstitution removes weighing and dilution errors from experiments comparing formats or routes.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/semax-nasal-spray/