# SLU-PP-332

> Pan-ERR agonist small molecule used as an exercise-mimetic research probe

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/slu-pp-332/
- Brand: Peptide Medix EU
- Category: [Fat-Loss & Metabolic Peptides](https://peptidemedixeu.com/en/collections/fat-loss-peptides/)
- Purity: ≥99% by HPLC; lot-matched COA available
- CAS number: 2098486-97-2
- from €76 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 5 mg | €76 | SLU-PP-332-5-MG |
| 10 mg | €131 | SLU-PP-332-10-MG |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **CAS number:** 2098486-97-2
- **Molecular weight:** 290.27 g/mol
- **Form:** Lyophilized powder, sealed glass vial with flip-off seal
- **Purity:** ≥99% by HPLC; lot-matched COA available
- **Available sizes:** 5 mg, 10 mg
- **Solubility:** DMSO for concentrated stocks; dilute into assay medium or buffer
- **Compound class:** Small-molecule nuclear receptor agonist (non-peptide)
- **Molecular target:** Estrogen-related receptors ERR alpha, beta and gamma
- **Research areas:** Mitochondrial biogenesis, fatty-acid oxidation, muscle endurance transcription
- **Evidence base:** Cell culture and rodent studies only; no human data published
- **Storage (solid):** −20 °C, sealed and protected from light and moisture
- **Storage (in solution):** 2–8 °C, protected from light; use within the study window

## Description

SLU-PP-332 is a synthetic small molecule — not a peptide — that switches on all three estrogen-related receptors (ERRα, ERRβ and ERRγ). These orphan nuclear receptors control the gene programme behind mitochondrial biogenesis, oxidative phosphorylation and fatty-acid oxidation in muscle. Their name is misleading: they neither are estrogen receptors nor bind estradiol, having been named for a resemblance in sequence, and they work mainly together with PGC-1-family coactivators.

Interest in the compound arose because ERR activation turns on many genes that endurance training also induces, which is why papers have called it an “exercise mimetic”. Researchers add an important qualification: all published data come from cell systems and mice, with no human evidence at all. That gap is precisely what makes it a good probe — it lets labs work out which parts of the exercise-induced transcriptional response depend on ERR signalling and which do not.

## Frequently asked questions

### Does SLU-PP-332 bind estrogen receptors?

No. Estrogen-related receptors resemble estrogen receptors in sequence but ignore estradiol and function differently: they are constitutively active orphan nuclear receptors that regulate oxidative-metabolism genes, chiefly via PGC-1 coactivators.

### Which analytical documents come with it?

Every lot is HPLC-tested to ≥99% purity, and its certificate of analysis is available, referencing the vial number you receive so the purity data map onto the exact material used.

### Why dissolve it in DMSO rather than water?

Being a small hydrophobic molecule, not a peptide, it dissolves poorly in water. The usual approach is a concentrated DMSO stock diluted into medium, with vehicle-matched controls in every condition.

### How is it stored?

Keep the sealed solid at −20 °C away from light and moisture. Prepared stocks go at 2–8 °C in the dark and should be used within your documented study period; aliquot them so they aren't warmed and cooled repeatedly.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/slu-pp-332/