# TB-500 + GHK-Cu

> 10 mg TB-500 and 50 mg GHK-Cu co-lyophilised in one research vial

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/tb-500-ghk-cu/
- Brand: Peptide Medix EU
- Category: [Recovery Blends](https://peptidemedixeu.com/en/collections/recovery-blends/)
- Purity: ≥99% by HPLC per component; lot-matched COA available
- from €127 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 60 mg · (10/50) | €127 | TB-500-GHK-CU-60-MG-10-50 |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **Peptide class:** Actin-binding thymosin fragment combined with a copper-binding matrix tripeptide
- **Form:** Co-lyophilized blue powder blend, sealed glass vial with crimped stopper
- **Purity:** ≥99% by HPLC per component; lot-matched COA available
- **Available sizes:** 60 mg total — 10 mg TB-500 / 50 mg GHK-Cu
- **Solubility:** Bacteriostatic or sterile water; avoid chelating buffers that strip copper
- **Storage (lyophilized):** −20 °C, sealed and protected from light and moisture
- **Storage (reconstituted):** 2–8 °C, protected from light, used within the study window
- **Components:** TB-500 (thymosin beta-4 fragment 17–23) and GHK-Cu (copper tripeptide-1)
- **Blend ratio:** 1:5 TB-500 to GHK-Cu by mass
- **TB-500 CAS number:** 885340-08-9
- **TB-500 formula and mass:** C38H68N10O14, 889.02 g/mol
- **TB-500 sequence:** Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln
- **GHK-Cu CAS number:** 89030-95-5
- **GHK-Cu formula and mass:** C14H24N6O4·Cu, 403.93 g/mol
- **GHK-Cu sequence:** Gly-His-Lys, complexed with copper(II)
- **Colour:** Blue in powder and in solution — an indicator of copper coordination
- **Research areas:** Cell migration, wound closure, angiogenesis, collagen and glycosaminoglycan synthesis, dermal and follicle models

## Description

The two peptides in this vial tackle tissue remodelling from opposite ends. TB-500 is the acetylated heptapeptide matching residues 17–23 of thymosin beta-4 — the actin-binding domain of a 43-amino-acid protein that sequesters G-actin — and is studied mainly for cell migration and wound closure. GHK-Cu, the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine first isolated from human plasma in the 1970s, is studied for extracellular-matrix synthesis, collagen and glycosaminoglycan production and copper-dependent enzyme chemistry.

The fill totals 60 mg: 10 mg TB-500 and 50 mg GHK-Cu. The uneven split reflects how each is used, not a statement about relative potency — GHK-Cu is conventionally handled in much larger amounts than short synthetic fragments in matrix and skin models. Both peptides are synthesised and purified to ≥99% by reversed-phase HPLC before they are combined, so the lot's certificate of analysis reports each one separately instead of describing the mixture as a single substance.

## Frequently asked questions

### What amount of each peptide does the vial contain?

10 mg TB-500 and 50 mg GHK-Cu in a 60 mg fill — a 1:5 mass ratio. The exact loading appears on the label and on the lot certificate, which lists the two peptides individually rather than treating the blend as one substance.

### What makes the powder blue?

GHK-Cu is a copper(II) complex, and the bound copper colours both the lyophilised cake and the dissolved solution a distinct blue. That makes a handy in-process check: a steady blue means the complex is intact, while fading or a green tinge suggests the copper binding has been disrupted.

### Which diluent should I use?

Bacteriostatic water for vials drawn from repeatedly, sterile water for single-use solutions. Steer clear of EDTA buffers, strong reducing agents and chelator-rich media, which can pull copper from the GHK-Cu and change what you are actually testing.

### Is a certificate of analysis provided?

Yes. Each vial links to a lot COA covering both peptides — HPLC purity of ≥99% for each plus identity by mass spectrometry. Please quote the lot number printed on the vial when asking for it.

### Why use them together rather than in separate experiments?

They act at different stages of remodelling — cytoskeletal migration on one side, matrix biosynthesis on the other — so researchers often want both present at a fixed ratio. A co-lyophilised vial saves a second reconstitution, an extra stopper puncture and another source of pipetting variation between arms.

### Can it be used on humans or as a cosmetic?

No. Both peptides are supplied as research chemicals in a lab vial. The blend is not a medicine, cosmetic or supplement and is not authorised for any use in any circumstances.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/tb-500-ghk-cu/