# Tesamorelin

> GHRH(1–44) research analogue carrying a trans-3-hexenoyl group

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/tesamorelin/
- Brand: Peptide Medix EU
- Category: [GHRH Analogs](https://peptidemedixeu.com/en/collections/ghrh-peptides/)
- Purity: ≥99% by HPLC; lot-matched COA available
- CAS number: 218949-48-5
- from €72 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 5 mg | €72 | TESAMORELIN-5-MG |
| 10 mg | €123 | TESAMORELIN-10-MG |
| 20 mg | €191 | TESAMORELIN-20-MG |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **CAS number:** 218949-48-5
- **Molecular formula:** C221H366N72O67S
- **Molecular weight:** 5135.86 g/mol
- **Amino acid sequence:** trans-3-hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2
- **Chain length:** 44 amino acids, N-terminally acylated, C-terminal amide
- **Peptide class:** GHRH analogue (GHRH-R agonist)
- **Form:** Lyophilized powder, sealed glass vial
- **Purity:** ≥99% by HPLC; lot-matched COA available
- **Available sizes:** 5 mg, 10 mg, 20 mg
- **Storage (lyophilized):** −20 °C, sealed and protected from light and moisture
- **Storage (reconstituted):** 2–8 °C, used within the study window
- **Key modification:** trans-3-hexenoyl group on the N-terminal tyrosine
- **Research areas:** Somatotropic axis signalling, visceral adipose metabolism, peptide stability

## Description

Tesamorelin is a man-made version of growth hormone-releasing hormone (GHRH) that keeps all 44 residues of the human sequence and adds a trans-3-hexenoyl fatty acyl group to the tyrosine at position 1. That one lipophilic cap is the entire design idea. Native GHRH is quickly trimmed at its free N-terminus by dipeptidyl peptidase-4, and researchers study how capping this spot holds off the enzyme without harming how the receptor recognises the peptide.

Weighing roughly 5136 g/mol, it is among the biggest members of the GHRH family offered for research — far longer than shortened fragments like sermorelin or modified GRF 1-29. It is assembled on solid phase, cleaned up by reversed-phase HPLC and delivered as a freeze-dried powder. Labs rely on it as a durable, well-described GHRH receptor agonist for work on endocrine signalling, and for comparative studies of fat-tissue metabolism in animals.

## Frequently asked questions

### What is tesamorelin?

It is synthetic GHRH in its full 44-amino-acid length, carrying a trans-3-hexenoyl cap on the N-terminus. Researchers employ it as a GHRH receptor agonist with improved stability in models of endocrine signalling and metabolism.

### How does it compare with sermorelin?

Sermorelin covers only residues 1–29 of GHRH and has no modifications. Tesamorelin covers all of residues 1–44 and adds an acyl cap at the start of the chain. Comparing the two in vitro shows what chain length and an end-protecting group each contribute to resisting enzymes and switching on the receptor.

### Does it come with a Certificate of Analysis?

Yes. Each lot's identity and ≥99% purity are HPLC-tested by an independent laboratory, and you can request the corresponding certificate. Compare its lot number with the one printed on your vial so your records refer to exactly the batch delivered.

### How stable is tesamorelin once reconstituted?

In solution tesamorelin degrades much faster than as a dry powder. Refrigerate it at 2–8 °C, keep it dark, and finish it within the time frame your lab has checked; dividing it into aliquots before storage avoids the losses that come with freezing and thawing repeatedly.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/tesamorelin/