# Thymosin Alpha-1 Nasal Spray

> Thymosin alpha-1 ready-dissolved for nasal research — metered pumps, 15 mL or 30 mL

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/thymosin-alpha-1-nasal-spray/
- Brand: Peptide Medix EU
- Category: [Nasal Peptide Sprays](https://peptidemedixeu.com/en/collections/nasal-peptide-sprays/)
- from €123 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 15 mL | €123 | THYMOSIN-ALPHA-1-NASAL-SPRAY-15-ML |
| 30 mL | €204 | THYMOSIN-ALPHA-1-NASAL-SPRAY-30-ML |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **Amino acid sequence:** Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn
- **Chain length:** 28 amino acids, N-terminally acetylated
- **Peptide class:** Thymic immunomodulatory peptide
- **Form:** Pre-mixed aqueous solution in an amber bottle fitted with a metered nasal pump
- **Available sizes:** 15 mL, 30 mL
- **Fill note:** Both sizes are filled from the same bulk solution; the 30 mL bottle holds twice the volume at the same nominal concentration, and the peptide loading for your lot is printed on the label
- **Active component:** Thymosin alpha-1, ≥99% by HPLC; lot-matched COA available
- **CAS number (active):** 62304-98-7
- **Molecular formula (active):** C129H215N33O55
- **Molecular weight (active):** 3108.30 g/mol
- **Parent protein:** Prothymosin alpha (residues 1–28)
- **Vehicle:** Preserved aqueous vehicle suitable for multi-actuation handling; clear and colourless when fresh
- **Reconstitution:** None required — supplied ready to dispense
- **Research areas:** Intranasal peptide delivery, nasal mucosal absorption, T cell maturation, Toll-like receptor signalling, antiviral and adjuvant models
- **Storage:** 2–8 °C upright, protected from light; do not freeze the filled bottle

## Description

This spray contains the identical 28-residue thymus peptide found in our freeze-dried vial, but dissolved in a water-based vehicle with a preservative and filled into a brown glass bottle with a metering pump for the nose. Thymosin alpha-1 is the 1–28 fragment of prothymosin alpha — its first 28 amino acids — with an acetyl group on the first one; it was originally isolated from thymus tissue and has been researched for decades for its role in how T cells mature and in innate immune signalling.

Why a spray? As a powder, the molecule is awkward to handle in small amounts: at around 3.1 kDa it is very hydrophilic and strongly charged, so sub-milligram weighings easily lose material to static and vial walls. The ready-mixed format removes reconstitution altogether and gives every press the same nominal peptide load — valuable for studies of mucosal delivery, nasal deposition and solution stability, where a reliable starting concentration counts for more than a custom dilution.

## Frequently asked questions

### Spray versus lyophilised vial — what changes?

The molecule is identical — the acetylated 28-residue peptide, HPLC purity ≥99%. What changes is the format: the spray is supplied already dissolved in a preserved water-based liquid with a metering pump, so there's no weighing, no reconstitution and no transferring powder, and every spray contains the same nominal amount.

### How pure is the peptide in the spray?

The bulk peptide is HPLC-tested to ≥99% before it is formulated, and the lot certificate is available on request. The COA relates to the peptide input; your fill lot's label shows the nominal peptide loading.

### How do the 15 mL and 30 mL bottles differ?

Only the amount of liquid. Both are filled from one batch of solution at one nominal strength, so the 30 mL bottle simply holds twice as much — and picking it means fewer changes of lot during a longer study.

### Must the bottle be refrigerated?

Yes: store it upright at 2–8 °C, protected from light. Peptides break down faster in solution than when freeze-dried, and keeping them cold slows the loss of amide groups and oxidation. Never freeze a filled bottle — neither the glass nor the pump is made to survive freezing and thawing.

### Can I dilute or transfer the solution for assays?

For analysis, researchers normally draw off a portion into a separate container rather than spraying it out. If you dilute it, write down which diluent you used, the pH of the buffer and the final concentration, because how stable this peptide stays in solution depends on pH and temperature.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/thymosin-alpha-1-nasal-spray/