# Tirzepatide + Vitamin B12

> Dual GIP/GLP-1 agonist peptide combined with methylcobalamin in one vial

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/tirzepatide-b12/
- Brand: Peptide Medix EU
- Category: [Weight Management Blends](https://peptidemedixeu.com/en/collections/weight-management-blends/)
- from €119 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 10 mg | €119 | TIRZEPATIDE-B12-10-MG-B12 |
| 20 mg | €191 | TIRZEPATIDE-B12-20-MG-B12 |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **Peptide class:** Acylated dual GIP/GLP-1 receptor agonist (twincretin), 39 residues
- **Form:** Lyophilized co-formulated powder, sealed glass vial with flip-off seal
- **Available sizes:** 10 mg tirzepatide + B12; 20 mg tirzepatide + B12
- **Component 1:** Tirzepatide — dual GIP/GLP-1 receptor agonist peptide
- **Component 2:** Methylcobalamin — methylated coenzyme form of vitamin B12
- **Purity (peptide):** ≥99% by HPLC; lot-matched COA available
- **CAS number (tirzepatide):** 2023788-19-2
- **Molecular formula (tirzepatide):** C225H348N48O68
- **Molecular weight (tirzepatide):** 4813.45 g/mol
- **CAS number (methylcobalamin):** 13422-55-4
- **Molecular formula (methylcobalamin):** C63H91CoN13O14P
- **Molecular weight (methylcobalamin):** 1344.38 g/mol
- **Research areas:** Incretin receptor signalling, energy balance and glycaemic models, cofactor co-formulation stability
- **Storage:** −20 °C lyophilized; 2–8 °C reconstituted, protected from light at all times

## Description

Two well-understood components share this vial: tirzepatide, a 39-residue acylated agonist of both GIP and GLP-1 receptors, and methylcobalamin, the methylated coenzyme form of vitamin B12. They are chemically unrelated and act through completely separate systems. Tirzepatide is a synthetic peptide built around a GIP backbone whose C20 fatty diacid chain gives it albumin binding and a long half-life in circulation; methylcobalamin is a deep-red cobalt corrinoid serving as cofactor for methionine synthase.

Such blends occur in compounding and research because the two parts address different variables of one experimental system: the incretin agonist drives the metabolic endpoints being studied, while B12 is a co-formulated cofactor that researchers may want to keep constant or manipulate. Combining them also changes the formulation science — the corrinoid is highly light-sensitive and colours the solution, which alters how the vial must be handled and how spectrophotometric data are read.

## Frequently asked questions

### What does the vial contain?

Tirzepatide — a 39-residue acylated dual GIP/GLP-1 receptor agonist — and methylcobalamin, vitamin B12's methylated coenzyme form. Unrelated chemically and acting via different systems, they are simply supplied together from one lyophilised preparation.

### How is it different from plain tirzepatide?

The peptide and its specifications are identical. What differs is the added methylcobalamin, which tints the reconstituted solution, makes it very light-sensitive and disturbs UV-based peptide quantification unless the two are separated chromatographically.

### Why is protection from light stressed so strongly?

Light breaks methylcobalamin's cobalt–carbon bond, and this photolysis is quick enough to change the preparation during normal bench work under bright lights. Amber containers, foil wrapping and minimal exposure are standard for any solution containing a corrinoid.

### Which purity documents are available?

An independent lab HPLC-tests the peptide component to ≥99% purity, and the lot certificate covering identity and purity is available on request. Keep it with your study records so material and data stay linked.

### In what sizes is it sold?

Two: 10 mg or 20 mg of tirzepatide, each with B12. The milligram figure refers to peptide content; the amount of cofactor is recorded in the lot documentation.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/tirzepatide-b12/