# Tirzepatide

> Research-grade 39-amino-acid peptide agonist of both GIP and GLP-1 receptors

All products are sold strictly for laboratory research use only. Not for human or veterinary use.

- Web page: https://peptidemedixeu.com/en/products/tirzepatide/
- Brand: Peptide Medix EU
- Category: [GLP-1 & Incretin Peptides](https://peptidemedixeu.com/en/collections/glp-1-peptides/)
- Purity: ≥99% by HPLC; lot-matched COA available
- CAS number: 2023788-19-2
- from €63 (EUR)

## Sizes and prices (EUR)

| Size | Price | SKU |
| --- | --- | --- |
| 5 mg | €63 | TIRZEPATIDE-5-MG |
| 10 mg | €102 | TIRZEPATIDE-10-MG |
| 15 mg | €136 | TIRZEPATIDE-15-MG |
| 20 mg | €170 | TIRZEPATIDE-20-MG |
| 30 mg | €242 | TIRZEPATIDE-30-MG |
| 60 mg | €391 | TIRZEPATIDE-60-MG |
| 100 mg | €433 | TIRZEPATIDE-100-MG |
| 10-vial kit · 10 x 10 mg | €884 | TIRZEPATIDE-10-VIAL-KIT-10-10-MG |

_Catalog prices at build time; the web page and checkout are authoritative._

## Specifications

- **CAS number:** 2023788-19-2
- **Molecular formula:** C225H348N48O68
- **Molecular weight:** 4813.45 g/mol
- **Peptide class:** Acylated dual GIP/GLP-1 receptor agonist (twincretin)
- **Form:** Lyophilized powder, sealed glass vial with flip-off seal
- **Purity:** ≥99% by HPLC; lot-matched COA available
- **Available sizes:** 5 mg, 10 mg, 15 mg, 20 mg, 30 mg, 60 mg, 100 mg
- **Solubility:** Bacteriostatic water; also soluble in dilute alkaline or phosphate buffers
- **Storage (lyophilized):** −20 °C, sealed and protected from light and moisture
- **Storage (reconstituted):** 2–8 °C, protected from light; use within the study window
- **Backbone length:** 39 amino acids, GIP-based sequence
- **Key modifications:** Aib substitutions, Lys20 conjugated to gamma-Glu-(AEEA)2-C20 diacid, C-terminal amide
- **Research areas:** Incretin receptor crosstalk, insulin secretion, adipose and energy-balance models

## Description

Tirzepatide is a synthetic peptide of 39 residues whose backbone derives from glucose-dependent insulinotropic polypeptide (GIP) and which was designed to activate two incretin receptors simultaneously. Alpha-aminoisobutyric acid residues stop dipeptidyl peptidase-4 from cutting it, and one lysine carries a gamma-glutamyl/AEEA linker attached to a C20 fatty diacid; the resulting reversible albumin binding explains why published pharmacokinetic studies find it so long-lived. Its C-terminus is amidated.

This dual-agonist design is what makes it valuable in the lab. Instead of looking at GLP-1 signalling alone, researchers use tirzepatide to explore how engaging GIP and GLP-1 receptors together alters cAMP kinetics, receptor trafficking and beta-arrestin recruitment, and how biased signalling at the GLP-1 receptor compares with balanced agonists. It features routinely as the comparator in studies of newer dual and triple agonists.

## Frequently asked questions

### How does tirzepatide differ from semaglutide?

Semaglutide is an analogue acting only at the GLP-1 receptor. Tirzepatide is built on a GIP backbone and activates both GIP and GLP-1 receptors, so labs use it to see how combined incretin-receptor engagement changes signalling compared with a single-receptor agonist.

### Which purity data and documents come with it?

Every lot is HPLC-tested to ≥99%, with identity confirmed by mass spectrometry, and its certificate is available — referenced to the vial number shipped so your results can be traced to your order.

### How is it stored before and after reconstitution?

Before: sealed at −20 °C, away from light and humidity. After: refrigerated at 2–8 °C in the dark and used within your documented study period. Aliquot so the stock isn't frozen and thawed repeatedly.

### Does it come sterile and ready to use?

It comes as lyophilised powder in a sealed vial, not as a finished solution. Your lab reconstitutes it under its own aseptic procedures and validates the solution for the assay or model you intend to use.

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All products offered on this website are intended solely for in-vitro laboratory research and development by qualified professionals. They are not drugs, foods, cosmetics or dietary supplements, and are not intended to diagnose, treat, cure or prevent any disease. Products must not be introduced into humans or animals in any manner. By purchasing, you confirm that you are a qualified researcher and accept full responsibility for handling and storage in accordance with applicable laws.

Peptide Medix EU · https://peptidemedixeu.com/en/products/tirzepatide/