- Each component assayed to ≥99% (HPLC); per-lot COA on request
- Certificate of analysis tied to your lot number
- Tracked EU delivery, dispatched the next working day
CJC-1295 DAC + Ipamorelin
Albumin-binding GHRH analogue co-lyophilised with the selective GHS-R1a agonist ipamorelin
In stock2 formats available
€110Range €110 – €191
This listing is currently unavailable. Contact us and we will tell you when it is back or suggest an equivalent.
Ask about this listing or request its COA- FormLyophilized powder, sealed glass vial with crimped stopper
- Research areasSomatotroph signalling, GH pulse amplitude versus frequency, IGF-1 dynamics, receptor desensitisation
For laboratory research use only. Sold exclusively for in-vitro laboratory research by qualified professionals. Not for human or veterinary use, and not a medicine, food, cosmetic or dietary supplement. Terms and Conditions
Overview
Key facts
Two growth-hormone secretagogues are co-lyophilised in this vial in equal amounts by mass: CJC-1295 with DAC, a modified GRF(1-29) analogue fitted with a drug affinity complex, and ipamorelin, a pentapeptide that selectively activates the growth hormone secretagogue receptor.
- Purity
- ≥99% by HPLC per component; lot-matched COA available
- Form
- Lyophilized powder, sealed glass vial with crimped stopper
- Storage
- Lyophilized: −20 °C, sealed, protected from light and moisture. Reconstituted: 2–8 °C within the study window.
- Available sizes
- 10 mg · (5/5) · 20 mg · (10/10)
For research use only. Not for human consumption.
Two growth-hormone secretagogues are co-lyophilised in this vial in equal amounts by mass: CJC-1295 with DAC, a modified GRF(1-29) analogue fitted with a drug affinity complex, and ipamorelin, a pentapeptide that selectively activates the growth hormone secretagogue receptor. The 10 mg size contains 5 mg of each; the 20 mg size contains 10 mg of each.
This combination is a textbook design in somatotroph pharmacology because each peptide uses a different receptor. CJC-1295 DAC works through the GHRH receptor and boosts the size of the pituitary's secretory response, while ipamorelin acts at the ghrelin receptor — a distinct pathway that supplies the pulse. The DAC — a maleimidopropionyl group that bonds covalently to cysteine-34 of circulating albumin — lengthens the analogue's residence time enormously compared with the unconjugated form, so this blend gives a very different exposure profile from the No-DAC version.
What sets this listing apart
CJC-1295 DAC + Ipamorelin combines CJC-1295 with DAC and Ipamorelin in one listing (10/20 mg). Components that are also sold on their own are linked below, each with its own specification and COA.
Same compound, other listings
- CJC-1295 with DAC
- Ipamorelin
- CJC-1295 (No DAC) + Ipamorelin
- Growth Hormone Stack (CJC-1295 · Ipamorelin · Sermorelin vials)
- GH Peptide Starter Kit (CJC-1295 + Ipamorelin 10 mg · Bac Water · Syringes · Pads)
- Ipamorelin + GHRP-2
- Joint & Tendon Stack (BPC-157 · TB-500 · GHK-Cu · Ipamorelin vials)
- Lean Stack (AOD-9604 · MOTS-c · Tesamorelin · Ipamorelin)
Specifications
Supply & purity
- Form
- Lyophilized powder, sealed glass vial with crimped stopper
- Purity
- ≥99% by HPLC per component; lot-matched COA available
- Available sizes
- 10 mg total (5 mg / 5 mg); 20 mg total (10 mg / 10 mg)
- Solubility
- Bacteriostatic or sterile water; both peptides dissolve readily
Additional detail
- Product type
- Co-lyophilized two-peptide blend, single vial
- Blend ratio
- 1:1 CJC-1295 DAC to ipamorelin by mass
- CJC-1295 DAC
- CAS 863288-34-0 · C165H269N47O46 · 3647.28 g/mol
- CJC-1295 DAC structure
- Modified GRF(1-29) (D-Ala2, Gln8, Ala15, Leu27) extended with Lys30-maleimidopropionamide
- Ipamorelin
- CAS 170851-70-4 · C38H49N9O5 · 711.85 g/mol
- Ipamorelin sequence
- Aib-His-D-2-Nal-D-Phe-Lys-NH2
- Molecular targets
- GHRH receptor (CJC-1295 DAC) and growth hormone secretagogue receptor 1a (ipamorelin)
- Conjugation chemistry
- Maleimide–thiol addition of the DAC group to cysteine-34 of serum albumin
- Research areas
- Somatotroph signalling, GH pulse amplitude versus frequency, IGF-1 dynamics, receptor desensitisation
- Storage
- Lyophilized: −20 °C, sealed, protected from light and moisture. Reconstituted: 2–8 °C within the study window.
Questions about CJC-1295 DAC + Ipamorelin
What does this vial contain?
A single lyophilised cake containing both peptides 1:1 by mass — 5 mg each in the 10 mg size, 10 mg each in the 20 mg size. There is no diluent, carrier or preservative, so you set the working concentration yourself when reconstituting.
How is it different from the CJC-1295 No DAC + Ipamorelin blend?
In the DAC version a maleimidopropionyl group attaches covalently to albumin, stretching the reported half-life from minutes to days. The No-DAC blend gives brief, separate bursts of signalling. Studies contrasting sustained receptor occupancy with pulsed stimulation usually include both.
What is the point of combining a GHRH analogue with a ghrelin-receptor agonist?
They target different receptors — CJC-1295 DAC the GHRH receptor, ipamorelin GHS-R1a, which additionally affects somatostatin tone. Using both lets researchers test whether the two pathways add up or act synergistically on somatotroph output in their model.
Is there a certificate of analysis?
Yes. Both peptides are HPLC-assayed to a ≥99% specification with identity confirmed by mass spectrometry, and every blend lot has its own certificate covering the two components. You can ask for the current COA before ordering.
Which diluent should be used?
Use bacteriostatic water for vials that will be drawn from several times, or sterile water for single use. Introduce it slowly along the glass and swirl until the cake has dissolved, giving a clear, colourless solution. Do not shake and do not use acidic diluents.
How do I store the reconstituted blend?
Refrigerate at 2–8 °C away from light, withdraw aseptically and use it within the period set by your protocol. Keep the vial upright, don't let it warm to room temperature repeatedly, and discard it if it turns cloudy or coloured or shows particles.
