- HPLC purity ≥99%, with a COA for each lot on request
- Certificate of analysis tied to your lot number
- Tracked EU delivery, dispatched the next working day
Ipamorelin
Selective GHS-R1a pentapeptide agonist, Aib-His-D-2-Nal-D-Phe-Lys-NH2
In stock3 formats availableCAS 170851-70-4
€34Range €34 – €63
This listing is currently unavailable. Contact us and we will tell you when it is back or suggest an equivalent.
Ask about this listing or request its COA- FormLyophilized powder, sealed glass vial
- Mol. weight711.85 g/mol
- Research areasGHS-R1a signalling, secretagogue selectivity, gastrointestinal motility models
For laboratory research use only. Sold exclusively for in-vitro laboratory research by qualified professionals. Not for human or veterinary use, and not a medicine, food, cosmetic or dietary supplement. Terms and Conditions
Overview
Key facts
Ipamorelin is a five-residue synthetic peptide designed to activate selectively the growth hormone secretagogue receptor GHS-R1a — the receptor of the natural hormone ghrelin.
- CAS number
- 170851-70-4
- Molecular formula
- C38H49N9O5
- Molecular weight
- 711.85 g/mol
- Amino acid sequence
- Aib-His-D-2-Nal-D-Phe-Lys-NH2
- Purity
- ≥99% by HPLC; lot-matched COA available
- Form
- Lyophilized powder, sealed glass vial
- Storage
- −20 °C, sealed and protected from light and moisture
- Available sizes
- 2 mg · 5 mg · 10 mg
For research use only. Not for human consumption.
Ipamorelin is a five-residue synthetic peptide designed to activate selectively the growth hormone secretagogue receptor GHS-R1a — the receptor of the natural hormone ghrelin. Its sequence, Aib-His-D-2-Nal-D-Phe-Lys-NH2, squeezes a non-natural aminoisobutyric acid, two D-amino acids and a C-terminal amide into five positions, producing a compact molecule of roughly 712 g/mol that ordinary proteases struggle to break down.
Ipamorelin stood out in the peptide literature because of how selective it is. Older secretagogues like GHRP-6 and hexarelin were found to shift cortisol, prolactin and appetite signalling as well, whereas ipamorelin gave a comparatively clean growth hormone response in animal models. That is why it became a standard tool for isolating GHS-R1a signalling from the wider neuroendocrine background.
What sets this listing apart
Ipamorelin – vial, 2/5/10 mg. Lyophilized powder, sealed glass vial. Other Ipamorelin listings differ in format, fill or combination partners; the specification and COA always refer to the listing you order.
Same compound, other listings
- CJC-1295 DAC + Ipamorelin
- CJC-1295 (No DAC) + Ipamorelin
- Growth Hormone Stack (CJC-1295 · Ipamorelin · Sermorelin vials)
- GH Peptide Starter Kit (CJC-1295 + Ipamorelin 10 mg · Bac Water · Syringes · Pads)
- Ipamorelin + GHRP-2
- Joint & Tendon Stack (BPC-157 · TB-500 · GHK-Cu · Ipamorelin vials)
- Lean Stack (AOD-9604 · MOTS-c · Tesamorelin · Ipamorelin)
- Prime Stack (Tesamorelin · Ipamorelin · MOTS-c vials)
Specifications
Identity
- CAS number
- 170851-70-4
- Molecular formula
- C38H49N9O5
- Molecular weight
- 711.85 g/mol
- Amino acid sequence
- Aib-His-D-2-Nal-D-Phe-Lys-NH2
- Chain length
- 5 residues, C-terminal amide
- Peptide class
- Growth hormone releasing peptide (GHRP), GHS-R1a agonist
Supply & purity
- Form
- Lyophilized powder, sealed glass vial
- Purity
- ≥99% by HPLC; lot-matched COA available
- Available sizes
- 2 mg, 5 mg, 10 mg
Handling & storage
- Storage (lyophilized)
- −20 °C, sealed and protected from light and moisture
Additional detail
- Unnatural residues
- Aib (2-aminoisobutyric acid), D-2-naphthylalanine, D-phenylalanine
- Primary target
- Growth hormone secretagogue receptor 1a (ghrelin receptor)
- Research areas
- GHS-R1a signalling, secretagogue selectivity, gastrointestinal motility models
Questions about Ipamorelin
What is ipamorelin?
A synthetic five-amino-acid agonist of GHS-R1a, the growth hormone secretagogue receptor that ghrelin normally activates. Labs use it as a selective reference compound to study secretagogue signalling independently of the GHRH pathway.
What makes ipamorelin “selective”?
In comparative animal work it released growth hormone without the accompanying shifts in cortisol, ACTH and prolactin seen with GHRP-6 and hexarelin. This narrower profile lets researchers credit their observations to GHS-R1a activation instead of broad neuroendocrine stimulation.
How is it different from a GHRH analogue?
Ipamorelin works on the ghrelin receptor GHS-R1a, which couples to Gq and triggers calcium signalling; sermorelin and CJC-1295 act on the Gs-coupled GHRH receptor and raise cyclic AMP. Because these are separate pathways, combination experiments are common in vitro.
Is its purity independently verified?
Yes. An independent lab confirms identity and ≥99% purity by HPLC for each lot, and the matching Certificate of Analysis is available on request. Compare the vial's lot number with the certificate when entering it into your inventory.
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