- HPLC-assayed purity of ≥99%
- Certificate of analysis tied to your lot number
- Tracked EU delivery, dispatched the next working day
NAD+ Nasal Spray
Ready-mixed NAD+ research solution for intranasal work, 15 mL metered pump
In stock2 formats availableCAS 53-84-9
€123Range €123 – €191
This listing is currently unavailable. Contact us and we will tell you when it is back or suggest an equivalent.
Ask about this listing or request its COA- FormPre-mixed aqueous solution, 15 mL bottle with metered spray pump
- Mol. weight663.43 g/mol
- Research areasMitochondrial energy metabolism, sirtuin and PARP biology, NAD+ salvage pathway, intranasal delivery models
For laboratory research use only. Sold exclusively for in-vitro laboratory research by qualified professionals. Not for human or veterinary use, and not a medicine, food, cosmetic or dietary supplement. Terms and Conditions
Overview
Key facts
This is NAD+ (nicotinamide adenine dinucleotide) dissolved in water and ready for research use, in a 15 mL bottle topped with a metering pump.
- CAS number
- 53-84-9
- Molecular formula
- C21H27N7O14P2
- Molecular weight
- 663.43 g/mol
- Form
- Pre-mixed aqueous solution, 15 mL bottle with metered spray pump
- Storage
- 2–8 °C, upright, protected from light; do not freeze the filled bottle
- Available sizes
- 15 mL · 300 mg · 15 mL · 600 mg
For research use only. Not for human consumption.
This is NAD+ (nicotinamide adenine dinucleotide) dissolved in water and ready for research use, in a 15 mL bottle topped with a metering pump. NAD+ (CAS 53-84-9) is a coenzyme made of two nucleotides joined together; it carries electrons through glycolysis, the Krebs cycle and oxidative phosphorylation, and is also used up by sirtuin deacetylases, PARP DNA-repair enzymes and CD38. Because these enzymes consume it all the time, the amount in a cell keeps shifting, and NAD+ supply has become one of the most intensively studied factors in research on mitochondria and cellular ageing.
With the spray, labs comparing different routes of administration no longer need to weigh, dissolve and sterile-filter powder before every session. It arrives ready-made at a known strength — either 300 mg or 600 mg of NAD+ in the 15 mL bottle, which is 20 or 40 mg per millilitre — well suited to nasal and mucosal-absorption models in which a consistent volume per spray matters more than a series of dilutions.
The nasal route is of interest because its epithelium is thin, well vascularised and close to olfactory and trigeminal pathways that have been investigated as ways around first-pass metabolism in the liver. Whether a particular molecule crosses in useful amounts depends on the compound and is still being researched — and NAD+, a large, very polar, negatively charged dinucleotide, is exactly why route-comparison studies continue.
What sets this listing apart
NAD+ Nasal Spray – nasal spray, 15 mL. Pre-mixed aqueous solution, 15 mL bottle with metered spray pump. Other NAD+ listings differ in format, fill or combination partners; the specification and COA always refer to the listing you order.
Same compound, other listings
Specifications
Identity
- CAS number
- 53-84-9
- Molecular formula
- C21H27N7O14P2
- Molecular weight
- 663.43 g/mol
Supply & purity
- Form
- Pre-mixed aqueous solution, 15 mL bottle with metered spray pump
- Available sizes
- 15 mL (300 mg total), 15 mL (600 mg total)
Additional detail
- Concentration
- 20 mg/mL (300 mg fill) or 40 mg/mL (600 mg fill)
- Purity (raw material)
- ≥99% by HPLC; lot-matched COA available
- Active compound
- NAD+ (nicotinamide adenine dinucleotide), free acid
- Compound class
- Pyridine dinucleotide coenzyme (small molecule, not a peptide)
- Research areas
- Mitochondrial energy metabolism, sirtuin and PARP biology, NAD+ salvage pathway, intranasal delivery models
- Reconstitution
- None required — supplied pre-mixed and ready to dispense
- Storage
- 2–8 °C, upright, protected from light; do not freeze the filled bottle
- Stability note
- NAD+ in aqueous solution degrades faster at warm or alkaline conditions — keep cold and use within the study window
Questions about NAD+ Nasal Spray
What amount of NAD+ is in a bottle?
Both versions come in the same 15 mL bottle: one contains 300 mg (20 mg/mL), the other 600 mg (40 mg/mL). The strength is printed on the label and stated again on the lot certificate, so you can verify your calculations against a documented value.
Is the NAD+ independently tested, with a COA I can see?
Yes. An outside laboratory checks the NAD+ used in the spray by HPLC, confirming at least 99% purity and verifying identity; the certificate for your batch is available. Make sure the lot on the bottle matches before you record data.
Must I reconstitute anything?
No — it arrives as a finished aqueous solution, with no weighing, solvent or filtering needed. Removing reconstitution variability from route-comparison experiments is the main reason labs choose the spray.
How do I store the bottle?
Refrigerate it at 2–8 °C, standing up and shielded from light, and never freeze it — freezing can crack the glass or ruin the pump. Dissolved NAD+ breaks down faster than the dry powder, so keep it cold and use it up within a short time.
Should NAD+ be regarded as a peptide?
No. NAD+ is a coenzyme built from two nucleotides — nicotinamide mononucleotide joined to adenosine monophosphate (C21H27N7O14P2). We list it among our research peptides because the same mitochondrial and longevity studies use both, not because they share a structure.
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