- HPLC-assayed purity of ≥99%
- Certificate of analysis tied to your lot number
- Tracked EU delivery, dispatched the next working day
Epitalon Nasal Spray
Ready-mixed Ala-Glu-Asp-Gly tetrapeptide solution in a metered spray bottle
In stock2 formats availableCAS 307297-39-8
€85Range €85 – €140
This listing is currently unavailable. Contact us and we will tell you when it is back or suggest an equivalent.
Ask about this listing or request its COA- FormPre-mixed aqueous solution in a bottle with metered spray pump
- Mol. weight390.35 g/mol
- Research areasTelomerase activity, circadian and pineal signalling, cellular senescence, intranasal delivery models
For laboratory research use only. Sold exclusively for in-vitro laboratory research by qualified professionals. Not for human or veterinary use, and not a medicine, food, cosmetic or dietary supplement. Terms and Conditions
Overview
Key facts
This is epitalon in intranasal form — the synthetic tetrapeptide Ala-Glu-Asp-Gly that Vladimir Khavinson's group designed as a short analogue of the pineal extract epithalamin.
- CAS number
- 307297-39-8
- Molecular formula
- C14H22N4O9
- Molecular weight
- 390.35 g/mol
- Amino acid sequence
- H-Ala-Glu-Asp-Gly-OH
- Form
- Pre-mixed aqueous solution in a bottle with metered spray pump
- Storage
- 2–8 °C, upright, protected from light; do not freeze the filled bottle
- Available sizes
- 15 mL · 30 mL
For research use only. Not for human consumption.
This is epitalon in intranasal form — the synthetic tetrapeptide Ala-Glu-Asp-Gly that Vladimir Khavinson's group designed as a short analogue of the pineal extract epithalamin. The molecule matches our lyophilised vials exactly (CAS 307297-39-8, C14H22N4O9, 390.35 g/mol), but it comes already dissolved in an aqueous vehicle in a bottle with a metered spray pump, so there is nothing to weigh, reconstitute or dissolve.
This format exists because the route of delivery is a research variable in its own right. Comparing intranasal and parenteral administration of small peptides is an established strand of the literature, driven by reports that low-molecular-weight compounds can travel from nose to brain via olfactory and trigeminal pathways. Epitalon's tiny size and excellent water solubility make it a convenient probe for such route comparisons, in addition to the telomerase, circadian and senescence topics it is usually studied for.
The peptide raw material is tested by an independent lab to ≥99% HPLC purity, and the lot's Certificate of Analysis can be viewed before purchase. The finished solution is filled into 15 mL and 30 mL bottles; each label states total peptide content and the amount delivered per spray.
What sets this listing apart
Epitalon Nasal Spray – nasal spray, 15/30 mL. Pre-mixed aqueous solution in a bottle with metered spray pump. Other Epitalon listings differ in format, fill or combination partners; the specification and COA always refer to the listing you order.
Same compound, other listings
Specifications
Identity
- CAS number
- 307297-39-8
- Molecular formula
- C14H22N4O9
- Molecular weight
- 390.35 g/mol
- Amino acid sequence
- H-Ala-Glu-Asp-Gly-OH
- Peptide class
- Synthetic bioregulator tetrapeptide
Supply & purity
- Form
- Pre-mixed aqueous solution in a bottle with metered spray pump
- Available sizes
- 15 mL, 30 mL
Additional detail
- Concentration
- Total peptide content and mg per actuation are printed on the bottle label
- Metered delivery
- Approximately 0.1 mL per actuation from the pump
- Purity (raw material)
- ≥99% by HPLC; lot-matched COA available
- Active peptide
- Epitalon (epithalon, AEDG peptide)
- Vehicle
- Aqueous solution with a preservative system suitable for a multi-actuation bottle
- Research areas
- Telomerase activity, circadian and pineal signalling, cellular senescence, intranasal delivery models
- Reconstitution
- None required — supplied pre-mixed and ready to dispense
- Storage
- 2–8 °C, upright, protected from light; do not freeze the filled bottle
Questions about Epitalon Nasal Spray
What distinguishes this from epitalon vials?
Nothing about the molecule — it is Ala-Glu-Asp-Gly, 390.35 g/mol, in both. What changes is the format: a ready-mixed aqueous solution in a metered spray bottle instead of lyophilised powder needing reconstitution, making it the convenient option for studies of the intranasal route.
How much epitalon is in a bottle?
Each label shows the lot number, the total peptide content and the dose per spray, and the lot's Certificate of Analysis documents both values. Bottles come in 15 mL and 30 mL sizes.
How do you verify purity?
The epitalon used to make the solution is tested by an independent lab using reverse-phase HPLC (≥99%), with mass spectrometry confirming the expected 390.35 g/mol. You can view the lot COA on this page before ordering.
Should the bottle be refrigerated?
Yes. As the peptide is already dissolved, keep the bottle at 2–8 °C, upright and in the dark, and never freeze it — freezing a filled spray bottle can break the pump and cause precipitation when it thaws.
Why are small peptides of interest for intranasal studies?
Molecules under about 1000 g/mol are the ones most investigated for nose-to-brain transport via olfactory and trigeminal routes. At 390.35 g/mol, epitalon falls comfortably within that range, so it appears in route-comparison studies as well as in its own research field.
