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SLU-PP-332
Pan-ERR agonist small molecule used as an exercise-mimetic research probe
In stock2 formats availableCAS 2098486-97-2
€76Range €76 – €131
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Ask about this listing or request its COA- FormLyophilized powder, sealed glass vial with flip-off seal
- Mol. weight290.27 g/mol
- Research areasMitochondrial biogenesis, fatty-acid oxidation, muscle endurance transcription
For laboratory research use only. Sold exclusively for in-vitro laboratory research by qualified professionals. Not for human or veterinary use, and not a medicine, food, cosmetic or dietary supplement. Terms and Conditions
Overview
Key facts
SLU-PP-332 is a synthetic small molecule — not a peptide — that switches on all three estrogen-related receptors (ERRα, ERRβ and ERRγ).
- CAS number
- 2098486-97-2
- Molecular weight
- 290.27 g/mol
- Purity
- ≥99% by HPLC; lot-matched COA available
- Form
- Lyophilized powder, sealed glass vial with flip-off seal
- Available sizes
- 5 mg · 10 mg
For research use only. Not for human consumption.
SLU-PP-332 is a synthetic small molecule — not a peptide — that switches on all three estrogen-related receptors (ERRα, ERRβ and ERRγ). These orphan nuclear receptors control the gene programme behind mitochondrial biogenesis, oxidative phosphorylation and fatty-acid oxidation in muscle. Their name is misleading: they neither are estrogen receptors nor bind estradiol, having been named for a resemblance in sequence, and they work mainly together with PGC-1-family coactivators.
Interest in the compound arose because ERR activation turns on many genes that endurance training also induces, which is why papers have called it an “exercise mimetic”. Researchers add an important qualification: all published data come from cell systems and mice, with no human evidence at all. That gap is precisely what makes it a good probe — it lets labs work out which parts of the exercise-induced transcriptional response depend on ERR signalling and which do not.
What sets this listing apart
SLU-PP-332 – vial, 5/10 mg. Lyophilized powder, sealed glass vial with flip-off seal. Other SLU-PP-332 listings differ in format, fill or combination partners; the specification and COA always refer to the listing you order.
Same compound, other listings
Specifications
Identity
- CAS number
- 2098486-97-2
- Molecular weight
- 290.27 g/mol
Supply & purity
- Form
- Lyophilized powder, sealed glass vial with flip-off seal
- Purity
- ≥99% by HPLC; lot-matched COA available
- Available sizes
- 5 mg, 10 mg
- Solubility
- DMSO for concentrated stocks; dilute into assay medium or buffer
Additional detail
- Compound class
- Small-molecule nuclear receptor agonist (non-peptide)
- Molecular target
- Estrogen-related receptors ERR alpha, beta and gamma
- Research areas
- Mitochondrial biogenesis, fatty-acid oxidation, muscle endurance transcription
- Evidence base
- Cell culture and rodent studies only; no human data published
- Storage (solid)
- −20 °C, sealed and protected from light and moisture
- Storage (in solution)
- 2–8 °C, protected from light; use within the study window
Questions about SLU-PP-332
Does SLU-PP-332 bind estrogen receptors?
No. Estrogen-related receptors resemble estrogen receptors in sequence but ignore estradiol and function differently: they are constitutively active orphan nuclear receptors that regulate oxidative-metabolism genes, chiefly via PGC-1 coactivators.
Which analytical documents come with it?
Every lot is HPLC-tested to ≥99% purity, and its certificate of analysis is available, referencing the vial number you receive so the purity data map onto the exact material used.
Why dissolve it in DMSO rather than water?
Being a small hydrophobic molecule, not a peptide, it dissolves poorly in water. The usual approach is a concentrated DMSO stock diluted into medium, with vehicle-matched controls in every condition.
How is it stored?
Keep the sealed solid at −20 °C away from light and moisture. Prepared stocks go at 2–8 °C in the dark and should be used within your documented study period; aliquot them so they aren't warmed and cooled repeatedly.
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