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Tadalafil — Research Liquid
Reference entry for a long-acting PDE5 inhibitor — 30 mg/mL solution, 30 mL bottle
In stock1 format availableCAS 171596-29-5
€46
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Ask about this listing or request its COA- FormClear solution in an amber bottle with a graduated dispenser
- Mol. weight389.40 g/mol
For laboratory research use only. Sold exclusively for in-vitro laboratory research by qualified professionals. Not for human or veterinary use, and not a medicine, food, cosmetic or dietary supplement. Terms and Conditions
Overview
Key facts
Tadalafil blocks phosphodiesterase type 5 (PDE5) selectively; this enzyme normally breaks down cGMP in the smooth muscle of blood vessels.
- CAS number
- 171596-29-5
- Molecular formula
- C22H19N3O4
- Molecular weight
- 389.40 g/mol
- Form
- Clear solution in an amber bottle with a graduated dispenser
- Storage
- Room temperature, upright, tightly closed and protected from light
- Available size
- 30 mL · 30 mg/mL
For research use only. Not for human consumption.
Tadalafil blocks phosphodiesterase type 5 (PDE5) selectively; this enzyme normally breaks down cGMP in the smooth muscle of blood vessels. The molecule is not a peptide but a compact heterocycle — a tetracyclic diketopiperazine built on a beta-carboline core, formula C22H19N3O4, molecular weight around 389.4 g/mol. Regulatory records know it mainly as the active substance in Cialis and Adcirca.
Its authorisations, as a matter of public record, cover erectile dysfunction and the urinary symptoms of an enlarged prostate (benign prostatic hyperplasia); pulmonary arterial hypertension is covered separately, under another brand name at another strength. The feature most discussed in the pharmacology literature is its plasma half-life, which is long compared with other PDE5 inhibitors. The 30 mg/mL solution in a 30 mL bottle shown on this page is listed purely for reference and analytical work.
Specifications
Identity
- CAS number
- 171596-29-5
- Molecular formula
- C22H19N3O4
- Molecular weight
- 389.40 g/mol
Supply & purity
- Form
- Clear solution in an amber bottle with a graduated dispenser
- Solubility
- Practically insoluble in water; soluble in DMSO and in organic solvents used for analytical work
Additional detail
- Listing type
- Prescription-only reference item; released only against valid authorisation
- Listed presentation
- 30 mL at 30 mg/mL
- Compound class
- Selective phosphodiesterase type 5 (PDE5) inhibitor
- Chemical description
- Tetracyclic beta-carboline-derived diketopiperazine with a methylenedioxyphenyl substituent
- Reference brand names
- Cialis (ED and BPH indications); Adcirca (pulmonary arterial hypertension)
- Mechanism
- Blocks cGMP hydrolysis by PDE5, prolonging nitric-oxide-driven smooth muscle relaxation
- Approved indications (regulatory fact)
- Erectile dysfunction; signs and symptoms of benign prostatic hyperplasia; pulmonary arterial hypertension
- Pharmacology note
- Long elimination half-life relative to sildenafil and vardenafil; PDE5-selective with modest PDE11 affinity
- Storage
- Room temperature, upright, tightly closed and protected from light
Questions about Tadalafil — Research Liquid
Can it be obtained without a prescription?
No. In the EU, as in the US and similar jurisdictions, tadalafil may only be supplied on prescription. This page exists as an entry in an institutional reference catalogue; we release material only when a licensed practitioner or accredited research institution provides valid authorisation.
For which conditions is tadalafil authorised?
Public regulatory records list erectile dysfunction and the urinary symptoms of benign prostatic hyperplasia; a different brand at a different strength is authorised for pulmonary arterial hypertension. We state this as fact, not as a recommendation of any use.
Do you provide a certificate of analysis?
Yes. Identity and purity are recorded on a certificate specific to each lot; give us the lot number and we will send it. For reference and analytical purposes, that lot-level paperwork is exactly what this listing offers.
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