- HPLC purity ≥99%, with a COA for each lot on request
- Certificate of analysis tied to your lot number
- Tracked EU delivery, dispatched the next working day
Vialox (Pentapeptide-3V)
GPRPA pentapeptide for research in postsynaptic nicotinic-receptor models
In stock1 format availableCAS 135679-88-8
€178
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Ask about this listing or request its COA- FormLyophilized powder, sealed glass vial
- Mol. weight495.58 g/mol
- Research areasNicotinic acetylcholine receptor models, postsynaptic signaling and contraction-associated assays
For laboratory research use only. Sold exclusively for in-vitro laboratory research by qualified professionals. Not for human or veterinary use, and not a medicine, food, cosmetic or dietary supplement. Terms and Conditions
Overview
Key facts
Most catalogues sell the synthetic pentapeptide Gly-Pro-Arg-Pro-Ala as Vialox; it is also listed as Pentapeptide-3V or Pentapeptide-3.
- CAS number
- 135679-88-8
- Molecular formula
- C21H37N9O5
- Molecular weight
- 495.58 g/mol
- Amino acid sequence
- Gly-Pro-Arg-Pro-Ala-OH (GPRPA)
- Purity
- ≥99% by HPLC; lot-matched COA available
- Form
- Lyophilized powder, sealed glass vial
- Storage
- −20 °C lyophilized, protected from light and moisture
- Available size
- 200 mg
For research use only. Not for human consumption.
Most catalogues sell the synthetic pentapeptide Gly-Pro-Arg-Pro-Ala as Vialox; it is also listed as Pentapeptide-3V or Pentapeptide-3. Its two prolines limit how the backbone can bend, and the arginine in the centre is positively charged near neutral pH. As a defined molecule it has the formula C21H37N9O5 and weighs 495.58 g/mol.
Research and cosmetic-science reviews describe Vialox as a small peptide investigated in postsynaptic nicotinic acetylcholine receptor and contraction models, frequently with curare-like antagonism proposed as the mechanism. Direct evidence is thin, and it must not be confused with botulinum toxin, tubocurarine or Syn-AKE, which differ both chemically and pharmacologically.
Each research vial is sealed and contains 200 mg of freeze-dried GPRPA. Every lot is analysed by HPLC and supported by its own certificate of analysis. This is neither a drug acting on the neuromuscular junction nor a finished cosmetic; it is meant solely for controlled laboratory experiments.
Specifications
Identity
- CAS number
- 135679-88-8
- Molecular formula
- C21H37N9O5
- Molecular weight
- 495.58 g/mol
- Amino acid sequence
- Gly-Pro-Arg-Pro-Ala-OH (GPRPA)
- Chain length
- 5 residues
- Peptide class
- Synthetic proline-rich pentapeptide
Supply & purity
- Form
- Lyophilized powder, sealed glass vial
- Purity
- ≥99% by HPLC; lot-matched COA available
- Solubility
- Water-soluble; neutral buffered systems are commonly used
Additional detail
- Available size
- 200 mg
- Also known as
- Vialox, Pentapeptide-3V, Pentapeptide-3
- Research areas
- Nicotinic acetylcholine receptor models, postsynaptic signaling and contraction-associated assays
- Storage
- −20 °C lyophilized, protected from light and moisture
Questions about Vialox (Pentapeptide-3V)
What sequence does Vialox have?
Gly-Pro-Arg-Pro-Ala — five residues, abbreviated GPRPA. Catalogues also list it as Pentapeptide-3V or Pentapeptide-3.
Is it the same as Syn-AKE?
No. Vialox is an ordinary pentapeptide with a defined sequence, whereas Syn-AKE is a chemically modified diaminobutyroyl benzylamide sold as its diacetate salt. Occupying a similar research niche doesn't make them the same chemical.
Does Vialox have anything to do with botulinum toxin?
Only in the broadest sense that both appear in contraction studies. Botulinum toxin is a large enzyme (a protease) that works in an entirely different way and carries an entirely different risk profile; Vialox is a peptide of just five residues and should never be described as equivalent.
Which purity documents are provided?
HPLC (reversed-phase) confirms at least 99% purity for release, and every lot has a certificate. The identity check should agree with the mass of free GPRPA.
How is Vialox stored?
Keep the unopened freeze-dried vial dry at −20 °C in the dark. Keep working solutions in the fridge for a set study period, and divide into portions if your schedule runs longer.
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