- HPLC-assayed purity of ≥99%
- Certificate of analysis tied to your lot number
- Tracked EU delivery, dispatched the next working day
MOTS-c Oral Capsules
MOTS-c in oral research capsules — 5 mg each, 30 per bottle
In stock1 format availableCAS 1627580-64-6
€97
This listing is currently unavailable. Contact us and we will tell you when it is back or suggest an equivalent.
Ask about this listing or request its COA- FormOral capsule in a sealed bottle with tamper-evident closure
- Mol. weight2174.55 g/mol
- Research areasAMPK signalling, one-carbon and folate metabolism, glucose and lipid handling, oral peptide stability and bioavailability, exercise physiology
For laboratory research use only. Sold exclusively for in-vitro laboratory research by qualified professionals. Not for human or veterinary use, and not a medicine, food, cosmetic or dietary supplement. Terms and Conditions
Overview
Key facts
MOTS-c is a 16-residue peptide encoded in the mitochondrial 12S rRNA gene instead of nuclear DNA, making it one of a handful of mitochondrial-genome peptides alongside humanin and the SHLPs.
- CAS number
- 1627580-64-6
- Molecular formula
- C101H152N28O22S2
- Molecular weight
- 2174.55 g/mol
- Amino acid sequence
- Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Purity
- ≥99% by HPLC; lot-matched COA available
- Form
- Oral capsule in a sealed bottle with tamper-evident closure
- Storage
- Cool, dry and dark; refrigeration extends shelf stability
- Available size
- 5 mg · 30 capsules
For research use only. Not for human consumption.
MOTS-c is a 16-residue peptide encoded in the mitochondrial 12S rRNA gene instead of nuclear DNA, making it one of a handful of mitochondrial-genome peptides alongside humanin and the SHLPs. Here it is offered as a fixed-dose oral capsule of 5 mg, thirty capsules per sealed bottle, made from peptide of ≥99% HPLC purity with a certificate of analysis for each lot.
The peptide is the same one found in our lyophilised vials: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg, C101H152N28O22S2, roughly 2174.55 g/mol. Studies link it to AMPK activation, the folate–methionine one-carbon cycle, the handling of glucose and lipids, and — under metabolic stress — movement into the nucleus, where it reportedly affects adaptive gene expression.
What sets this listing apart
MOTS-c Oral Capsules – capsules, 5 mg. Oral capsule in a sealed bottle with tamper-evident closure. Other MOTS-c listings differ in format, fill or combination partners; the specification and COA always refer to the listing you order.
Same compound, other listings
Specifications
Identity
- CAS number
- 1627580-64-6
- Molecular formula
- C101H152N28O22S2
- Molecular weight
- 2174.55 g/mol
- Amino acid sequence
- Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Chain length
- 16 amino acids
Supply & purity
- Form
- Oral capsule in a sealed bottle with tamper-evident closure
Additional detail
- Peptide per capsule
- 5 mg MOTS-c
- Available size
- 30 capsules (150 mg total peptide per bottle)
- Peptide purity
- ≥99% by HPLC; lot-matched COA available
- Active peptide
- MOTS-c, mitochondrial-derived peptide (MDP)
- Genomic origin
- Short open reading frame within the mitochondrial 12S rRNA gene
- Research areas
- AMPK signalling, one-carbon and folate metabolism, glucose and lipid handling, oral peptide stability and bioavailability, exercise physiology
- Storage
- Cool, dry and dark; refrigeration extends shelf stability
- Preparation required
- None — fixed unit content, no reconstitution step
Questions about MOTS-c Oral Capsules
What is the MOTS-c content per capsule?
Each capsule contains 5 mg of MOTS-c, and a sealed bottle holds 30 of them — 150 mg of peptide altogether. As the content is set during manufacture, study designs based on whole capsules need no weighing or reconstitution at all.
Can MOTS-c be absorbed when taken orally?
Probably very little of it. Peptides this large are usually broken down by stomach acid and gut enzymes and cross the intestinal wall poorly, so assume low absorption into the blood unless your own study proves otherwise. The capsules are meant for research on stability, formulation and effects within the gut — not as a replacement for injecting the peptide.
Is a certificate of analysis available?
Yes. The certificate for the peptide in your capsule batch reports ≥99% purity by HPLC and confirms identity by mass spectrometry. To request it, give us the lot number shown on the bottle label.
What does “mitochondrial-derived peptide” mean?
It means the peptide's gene lies in the mitochondria's own DNA — in a short reading frame — rather than in the cell nucleus. MOTS-c is encoded in the 12S rRNA gene; the best-known others of its kind are humanin and the SHLP peptides. Researchers study them as messages sent from mitochondria to the rest of the cell.
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