- HPLC purity ≥99%, with a COA for each lot on request
- Certificate of analysis tied to your lot number
- Tracked EU delivery, dispatched the next working day
KPV
Lys-Pro-Val — the C-terminal tripeptide of alpha-MSH, in lyophilised vials
In stock2 formats availableCAS 67727-97-3
€42Range €42 – €63
This listing is currently unavailable. Contact us and we will tell you when it is back or suggest an equivalent.
Ask about this listing or request its COA- FormLyophilized powder, sealed glass vial with crimped stopper
- Mol. weight342.43 g/mol
- Research areasInflammatory signalling, NF-kappa B pathway, intestinal and dermal inflammation models
For laboratory research use only. Sold exclusively for in-vitro laboratory research by qualified professionals. Not for human or veterinary use, and not a medicine, food, cosmetic or dietary supplement. Terms and Conditions
Overview
Key facts
KPV is a three-residue peptide — lysine, proline, valine — copying the final three amino acids of alpha-melanocyte-stimulating hormone.
- CAS number
- 67727-97-3
- Molecular formula
- C16H30N4O4
- Molecular weight
- 342.43 g/mol
- Amino acid sequence
- Lys-Pro-Val
- Purity
- ≥99% by HPLC; lot-matched COA available
- Form
- Lyophilized powder, sealed glass vial with crimped stopper
- Storage
- −20 °C, sealed and protected from light and moisture
- Available sizes
- 5 mg · 10 mg
For research use only. Not for human consumption.
KPV is a three-residue peptide — lysine, proline, valine — copying the final three amino acids of alpha-melanocyte-stimulating hormone. It is among the shortest sequences in current inflammation research, and that shortness is precisely what makes it useful: in cell studies the fragment keeps the anti-inflammatory character ascribed to the parent hormone but lacks the melanocortin-receptor activity behind alpha-MSH's effects on pigmentation.
We make it by solid-phase synthesis, purify it by reversed-phase HPLC to ≥99% and fill it as lyophilised powder into sealed glass vials of 5 mg or 10 mg. At only 342 g/mol, each milligram contains many more moles than a longer peptide would, so these vial sizes stretch a long way in plate-based or animal studies.
What sets this listing apart
KPV – vial, 5/10 mg. Lyophilized powder, sealed glass vial with crimped stopper. Other KPV listings differ in format, fill or combination partners; the specification and COA always refer to the listing you order.
Same compound, other listings
Specifications
Identity
- CAS number
- 67727-97-3
- Molecular formula
- C16H30N4O4
- Molecular weight
- 342.43 g/mol
- Amino acid sequence
- Lys-Pro-Val
- Chain length
- 3 amino acids (tripeptide)
- Peptide class
- Melanocortin-derived tripeptide; C-terminal fragment of alpha-MSH (11–13)
Supply & purity
- Form
- Lyophilized powder, sealed glass vial with crimped stopper
- Purity
- ≥99% by HPLC; lot-matched COA available
- Available sizes
- 5 mg, 10 mg
- Solubility
- Freely soluble in bacteriostatic or sterile water
Handling & storage
- Storage (lyophilized)
- −20 °C, sealed and protected from light and moisture
- Storage (reconstituted)
- 2–8 °C, protected from light, used within the study window
Additional detail
- Research areas
- Inflammatory signalling, NF-kappa B pathway, intestinal and dermal inflammation models
Questions about KPV
What is KPV?
A synthetic tripeptide of lysine, proline and valine that matches the last three residues of alpha-melanocyte-stimulating hormone. We supply it as a lyophilised research powder; it is chiefly studied in models of inflammatory signalling and intestinal epithelial function.
How is KPV different from alpha-MSH?
Alpha-MSH is a 13-residue hormone acting on melanocortin receptors, influencing both pigmentation and inflammation. KPV consists of only its last three residues; studies report that it retains the anti-inflammatory character without the receptor-driven pigmentation activity of the whole hormone.
Do you provide a certificate of analysis?
Yes. Each lot is analysed by reversed-phase HPLC to ≥99% purity, with mass confirmation of the expected 342.43 g/mol, and the certificate bearing your vial's lot number can be requested before or after you order.
Which size should I buy?
Both go far, because the peptide is so light: at 342 g/mol, one milligram contains many more moles than a milligram of a 30-residue peptide. Take 5 mg for pilots and 10 mg for longer series.
What solvent is KPV usually dissolved in?
Most labs use bacteriostatic or sterile water, in which the tripeptide dissolves easily to a clear solution; buffers are chosen when an assay needs controlled pH. Solvent choice is part of the study design and is up to the researcher.
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