- HPLC purity ≥99%, with a COA for each lot on request
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Tripeptide-29 (Gly-Pro-Hyp)
Collagen tripeptide Gly-Pro-Hyp for matrix, stability and enzyme studies
In stock1 format availableCAS 2239-67-0
€178
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Ask about this listing or request its COA- FormLyophilized powder, sealed glass vial
- Mol. weight285.30 g/mol
- Research areasCollagen hydrolysate composition, peptide transport, fibroblast models, glycation, oxidative stress and DPP-IV assays
For laboratory research use only. Sold exclusively for in-vitro laboratory research by qualified professionals. Not for human or veterinary use, and not a medicine, food, cosmetic or dietary supplement. Terms and Conditions
Overview
Key facts
Tripeptide-29 is glycyl-L-prolyl-L-hydroxyproline (Gly-Pro-Hyp) — a motif repeated throughout collagen and frequently found among the small peptides released when collagen is hydrolysed.
- CAS number
- 2239-67-0
- Molecular formula
- C12H19N3O5
- Molecular weight
- 285.30 g/mol
- Amino acid sequence
- Gly-Pro-Hyp (glycyl-prolyl-hydroxyproline)
- Purity
- ≥99% by HPLC; lot-matched COA available
- Form
- Lyophilized powder, sealed glass vial
- Storage
- −20 °C lyophilized; keep sealed and dry
- Available size
- 200 mg
For research use only. Not for human consumption.
Tripeptide-29 is glycyl-L-prolyl-L-hydroxyproline (Gly-Pro-Hyp) — a motif repeated throughout collagen and frequently found among the small peptides released when collagen is hydrolysed. The hydroxyproline is what distinguishes it from Gly-Pro-Pro, supplying the hydroxyl group that is central to many studies of collagen structure and peptide transport.
Its uses range from collagen-model stability and the uptake and metabolism of collagen-derived peptides to fibroblast responses to hydrolysate fractions, glycation and oxidative-stress assays, and in-vitro enzyme studies involving DPP-IV. Having one purified tripeptide lets researchers test whether an effect attributed to a complex collagen hydrolysate can really be reproduced by Gly-Pro-Hyp on its own.
It comes as a 200 mg lyophilised vial (CAS 2239-67-0, C12H19N3O5, 285.30 g/mol), HPLC-tested with lot documentation, and is meant solely for analytical, biochemical and cell-model research — not as a food, supplement, cosmetic or medicine.
Precise identity matters with this reagent. Gly-Pro-Hyp is often discussed alongside Pro-Hyp and Hyp-Gly — different molecules from the same hydrolysate literature — and hydroxyproline has its own stereocentre, so catalogue entries should specify 4-hydroxy-L-proline rather than just “Hyp”. Supplying the tripeptide as a single purified compound with documented HPLC purity is what lets it act as an analytical reference for quantifying mixed hydrolysate fractions.
Specifications
Identity
- CAS number
- 2239-67-0
- Molecular formula
- C12H19N3O5
- Molecular weight
- 285.30 g/mol
- Amino acid sequence
- Gly-Pro-Hyp (glycyl-prolyl-hydroxyproline)
- Chain length
- 3 residues
- Peptide class
- Collagen-derived imino-acid-rich tripeptide
Supply & purity
- Form
- Lyophilized powder, sealed glass vial
- Purity
- ≥99% by HPLC; lot-matched COA available
- Solubility
- Water-soluble
Additional detail
- Available size
- 200 mg
- Also known as
- Gly-Pro-Hyp, GPH, collagen tripeptide, Tripeptide-29
- Research areas
- Collagen hydrolysate composition, peptide transport, fibroblast models, glycation, oxidative stress and DPP-IV assays
- Storage
- −20 °C lyophilized; keep sealed and dry
Questions about Tripeptide-29 (Gly-Pro-Hyp)
What is Tripeptide-29?
The defined collagen tripeptide Gly-Pro-Hyp (glycyl-prolyl-hydroxyproline), one of the motifs and breakdown products that recur in collagen.
Is it the same thing as collagen hydrolysate?
No. A hydrolysate contains a multitude of peptides of varying length and sequence, whereas this vial holds one purified tripeptide — ideal as an analytical standard or single-agent control.
Why does hydroxyproline matter?
It is a hallmark of collagen and influences peptide shape, susceptibility to enzymes and how the peptide is detected. Note, though, that measuring total hydroxyproline cannot prove intact Gly-Pro-Hyp is present.
Which purity documents are provided?
It is released at ≥99% by HPLC with a certificate for the lot. For quantitative protocols, take into account any counter-ion or water content listed in the lot documentation.
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